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Title: | Ultrasound estimation of birthweight in twin pregnancy: comparison of biometry algorithms in the STORK multiple pregnancy cohort. |
Authors: | Khalil, A. D'Antonio, F. Dias, T. Cooper, D. Thilaganathan, B. Southwest Thames Obstetric Research Collaborative (STORK) |
Keywords: | Pregnancy, Twin |
Issue Date: | 2014 |
Publisher: | Wiley |
Citation: | Ultrasound in Obstetrics and Gynecology. 2014; 44(2): 210-20. |
Abstract: | OBJECTIVES: The aims of this study were first, to ascertain the accuracy of formulae for ultrasonographic birth-weight estimation in twin compared with singleton pregnancies and second, to assess the accuracy of sonographic examination in the prediction of birth-weight discordance in twinpregnancies. METHODS: This was a retrospective cohort study including both singleton and twin pregnancies. Routine biometry was recorded and estimated fetalweight (EFW) calculated using 33 different formulae. Only pregnancies that delivered within 48 h of the ultrasound scan were included (4280 singleton and 586 twin fetuses). Differences between the EFW and actual birth weight (ABW) were assessed by percentage error, accuracy in predictions within ± 10 % and ± 15% of error and use of the Bland-Altman method. The accuracy of prediction of the different cut-offs of birth-weight discordance intwin pregnancies was also assessed using the area under the receiver-operating characteristics curve (AUC). RESULTS: The overall mean absolute percentage error was ≤ 10 % for 25 formulae in singleton pregnancies compared with three formulae in twinpregnancies. The overall predictions within ± 10% and ± 15% of the ABW were 62.2% and 81.5% in singleton and 49.7% and 68.5% in twinpregnancies, respectively. When the formulae were categorized according to the biometric parameters included, those based on a combination of head, abdomen and femur measurements showed the lowest mean absolute percentage error, in both singleton and twin pregnancies. The predictive accuracy for 25% birth-weight discordance using the Hadlock 2 formula, as assessed by the AUC, was 0.87. CONCLUSIONS: Ultrasound estimation of birth weight is less accurate in twin than in singleton pregnancies. Formulae that include a combination of head, abdomen and femur measurements perform best in both singleton and twin pregnancies. |
Description: | Indexed in MEDLINE |
URI: | http://repository.kln.ac.lk/handle/123456789/2386 |
ISSN: | 0960-7692 (Print) 1469-0705 (Electronic) |
Appears in Collections: | Journal/Magazine Articles |
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