In-vitro Microbiological Study on; an Indigenous Mouthwash (Gandusha) for Periodontal Disease

Abstract

Gandusha is clinica.lly effective in the management of perindontal disease. This study is an in-vitro anaiysis on dctcrmining the antimicrobral efficacl of the drug using standard Antimicrohial Sensitivity Test agamst a fungtrl culture isolated from a patient. Thc test was periormed according to the Well diffusion method having 6 mm diameter uells on Sahouraud Dextrose Agar (SDA). Each rr-ell rvas ioaded rrith the test drug nrired in 20 pl of sterile distilled rvater and l'luconazole 2.5 mg/ ml was used as the posrtive control. Accordrng to the results the test drug sho*'ed lnhibitory Zone Diameter (lZD) ol 1-5 mm. Therclbre rt can be stiited that the test drug is more elI'ective than the positive control and the isolated culture is sensitive to the rest drug as it had shown a IZD of l9 mm while it is intermedtate sensitive for the positive control as 15 mm comes under Intermediate Sensitive range (l-5 - 18 mm). These results support the fact that the indigenous nrouth wash (Candusha) is efttctive rn the management ofpcriodontal disease.