Please use this identifier to cite or link to this item:
http://repository.kln.ac.lk/handle/123456789/20273
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Manamperi, M. | - |
dc.contributor.author | Jayamanne, B. D. W. | - |
dc.contributor.author | Somaratne, T. | - |
dc.contributor.author | Perera, N. | - |
dc.contributor.author | Fernando, L. | - |
dc.date.accessioned | 2019-05-30T06:53:54Z | - |
dc.date.available | 2019-05-30T06:53:54Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | BMC Research Notes.2019;12(1):214 | en_US |
dc.identifier.issn | 1756-0500 (Electronic) | - |
dc.identifier.uri | http://repository.kln.ac.lk/handle/123456789/20273 | - |
dc.description | indexed in MEDLINE | en_US |
dc.description.abstract | OBJECTIVE:Dengue haemorrhagic fever (DHF) is a major public health concern responsible for significant morbidity in both adult and paediatric populations in Sri Lanka. This study examined if persistent non structural protein 1 (NS1) antigen positivity beyond day 3 was predictive of the occurrence of dengue haemorrhagic fever. The patients were followed up during their in-hospital stay and the severity of the illness was classified according to the WHO classification. The NS1 antigen test was repeated after day 3 of the onset of illness, at least 2 days after the initial test. RESULTS: One hundred and fifty-seven patients were enrolled. Persistent NS1 antigen test positivity after day 3 of the illness was not predictive of subsequent development of DHF. Out of multiple other demographic and illness related factors assessed, only having a secondary dengue infection was associated with a high risk of DHF (relative risk = 3.077, 95% CI 1.361, 6.954). Persistent NS1 positivity on day 3 may not be indicative of disease severity. However results need to be confirmed by a larger study with quantitative NS1 testing. | en_US |
dc.language.iso | en | en_US |
dc.publisher | London : Biomed Central | en_US |
dc.subject | DHF prediction | en_US |
dc.title | Predictive value of persistent NS1 antigen positivity beyond 3rd day for dengue haemorrhagic fever in Sri Lankan children. | en_US |
dc.type | Article | en_US |
Appears in Collections: | Journal/Magazine Articles |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Dengue.pdf | 603.25 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.