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Title: Rotavirus infections with multiple emerging genotypes in Sri Lanka
Authors: Ahmed, K.
Batuwanthudawe, R.
Chandrasena, T.G.A.N.
Mitui, M.T.
Rajindrajith, S.
Galagoda, G.
Pun, S.B.
Uchida, R.
Kunii, O.
Moji, K.
Abeysinghe, N.
Nishizono, A.
Nakagomi, O.
Issue Date: 2010
Publisher: Springer-Verlag
Citation: Archives of Virology. 2010; 155(1): pp. 71-5
Abstract: Rotavirus diarrhea is an important cause of child mortality in developing countries, but studies on this diarrhea are scarce in Sri Lanka. A prospective study conducted in Sri Lanka on rotavirus infection among children in a hospital setting (n = 611) versus children residing in tsunami camps (n = 52) showed that prevalence of rotavirus infection was comparable, 21.9 and 20%, respectively. The hospital and camps were located in different districts. Analysis of the genotypes of 122 rotaviruses from the hospital and 12 from the camps indicated that G9P[8] was associated with 35 and 33%; G12P[8/nt] with 14.7 and 33%; G3P[8/4/nt] with 17 and 8% and G1P[8/4] with 6.5 and 16.7%. Rotaviruses with G2P[8/4/6] and G4P[8/4] were hospital-associated only, and some rotaviruses (9 and 8% from the hospital and the camps, respectively) were G- and P-nontypable. We conclude from the present study that multiple emerging genotypes were prevalent in Sri Lanka, and children in camps were at risk of developing diarrhea due to rotaviruses
Description: Indexed in MEDLINE
ISSN: 0304-8608 (Print)
1432-8798 (Electronic)
Appears in Collections:Journal/Magazine Articles

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