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DC Field | Value | Language |
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dc.contributor.author | Sanagapalli, S. | |
dc.contributor.author | Ko, Y. | |
dc.contributor.author | Kariyawasam, V. | |
dc.contributor.author | Ng, S.C. | |
dc.contributor.author | Tang, W. | |
dc.contributor.author | de Silva, H.J. | |
dc.contributor.author | Chen, M. | |
dc.contributor.author | Wu, K. | |
dc.contributor.author | Aniwan, S. | |
dc.contributor.author | Ng, K.K. | |
dc.contributor.author | Ong, D. | |
dc.contributor.author | Ouyang, Q. | |
dc.contributor.author | Hilmi, I. | |
dc.contributor.author | Simadibrata, M. | |
dc.contributor.author | Pisespongsa, P. | |
dc.contributor.author | Gopikrishna, S. | |
dc.contributor.author | Leong, R.W. | |
dc.contributor.author | IBD Sydney Organization and the asia-Pacific Crohn's Epidemiology Study (ACCESS) Group | |
dc.date.accessioned | 2019-01-03T04:52:36Z | |
dc.date.available | 2019-01-03T04:52:36Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Intestinal Research. 2018;16(3): 409-415 | en_US |
dc.identifier.issn | 2288-1956 (Electronic) | |
dc.identifier.issn | 1598-9100 (Print) | |
dc.identifier.issn | 1598-9100 (Linking) | |
dc.identifier.uri | http://repository.kln.ac.lk/handle/123456789/19267 | |
dc.description | en | |
dc.description | Indexed in Scopus; In PUBMED; Indexed in MEDLINE | en |
dc.description.abstract | BACKGROUND/AIMS: To examine the association between use of oral contraceptive pills (OCPs) and the risk of developing inflammatory bowel diseases (IBD), in a modern cohort. METHODS: A prospective nested case-control study across sites in the Asia-Pacific region was conducted; involving female IBD cases and asymptomatic controls. Subjects completed a questionnaire addressing questions related to OCP use. Primary outcome was the risk of development of IBD of those exposed to OCP versus non-exposure. Secondary outcomes were development of Crohn's disease (CD) versus ulcerative colitis (UC), and whether age of first use of OCP use may be associated with risk of IBD. RESULTS: Three hundred and forty-eight female IBD cases (41% CD, median age: 43 years) and 590 female age-matched controls were recruited. No significant association was found between OCP use and the risk of IBD (odds ratio [OR], 1.65; 95% confidence interval, 0.77-3.13; P=0.22), CD (OR, 1.55) or UC (OR, 1.01). The lack of association persisted when results were adjusted for age and smoking. IBD cases commenced OCP use at a younger age than controls (18 years vs. 20 years, P=0.049). CONCLUSIONS: In this large cohort of subjects from the Asia-Pacific region, we found a modest but not significantly increased risk of developing IBD amongst OCP users. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Korean Association for the Study of Intestinal Diseases | en_US |
dc.subject | Inflammatory Bowel Diseases | en_US |
dc.subject | Contraceptive Agents | en |
dc.subject | Contraceptive Agents, Hormonal | en |
dc.subject | Contraceptives, Oral | en |
dc.subject | Contraceptives, Oral-adverse effects | en |
dc.title | The Association between new generation oral contraceptive pill and the development of inflammatory bowel diseases | en_US |
dc.type | Article | en_US |
Appears in Collections: | Journal/Magazine Articles |
Files in This Item:
File | Description | Size | Format | |
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ir-16-409.pdf | 652.96 kB | Adobe PDF | View/Open |
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