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dc.contributor.authorKasturiratne, A.en_US
dc.contributor.authorWickremasinghe, A.R.en_US
dc.contributor.authorde Silva, N.en_US
dc.contributor.authorGunawardena, N.K.en_US
dc.contributor.authorPathmeswaran, A.en_US
dc.contributor.authorPremaratna, R.en_US
dc.contributor.authorSavioli, L.en_US
dc.contributor.authorLalloo, D.G.en_US
dc.contributor.authorde Silva, H.J.en_US
dc.date.accessioned2014-10-29T09:26:52Zen_US
dc.date.available2014-10-29T09:26:52Zen_US
dc.date.issued2008en_US
dc.identifier.citationPLoS Medicine. 2008; 5(11): e218en_US
dc.identifier.issn1549-1277 (Print)en_US
dc.identifier.issn1549-1676 (Electronic)en_US
dc.identifier.other10.1371/journal.pmed.0050218en_US
dc.identifier.urihttp://repository.kln.ac.lk/handle/123456789/1852en_US
dc.descriptionIndexed in MEDLINEen_US
dc.description.abstractBACKGROUND: Envenoming resulting from snakebites is an important public health problem in many tropical and subtropical countries. Few attempts have been made to quantify the burden, and recent estimates all suffer from the lack of an objective and reproducible methodology. In an attempt to provide an accurate, up-to-date estimate of the scale of the global problem, we developed a new method to estimate the disease burdendue to snakebites. METHODS AND FINDINGS: The global estimates were based on regional estimates that were, in turn, derived from data available for countries within a defined region. Three main strategies were used to obtain primary data: electronic searching for publications on snakebite, extraction of relevant country-specific mortality data from databases maintained by United Nations organizations, and identification of grey literature by discussion with key informants. Countries were grouped into 21 distinct geographic regions that are as epidemiologically homogenous as possible, in line with the GlobalBurden of Disease 2005 study (Global Burden Project of the World Bank). Incidence rates for envenoming were extracted from publications and used to estimate the number of envenomings for individual countries; if no data were available for a particular country, the lowest incidence rate within a neighbouring country was used. Where death registration data were reliable, reported deaths from snakebite were used; in other countries, deathswere estimated on the basis of observed mortality rates and the at-risk population. We estimate that, globally, at least 421,000 envenomings and 20,000 deaths occur each year due to snakebite. These figures may be as high as 1,841,000 envenomings and 94,000 deaths. Based on the fact thatenvenoming occurs in about one in every four snakebites, between 1.2 million and 5.5 million snakebites could occur annually. CONCLUSIONS: Snakebites cause considerable morbidity and mortality worldwide. The highest burden exists in South Asia, Southeast Asia, and sub-Saharan Africa. Comment in Estimating the global burden of snakebite can help to improve management. [PLoS Med. 2008]en_US
dc.publisherPublic Library of Scienceen_US
dc.source.urihttp://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.0050218en_US
dc.subjectSnake Bitesen_US
dc.subjectSnake Bites-epidemiologyen_US
dc.subjectEnvenomingen_US
dc.subjectAsiaen_US
dc.titleThe Global burden of snakebite: a literature analysis and modelling based on regional estimates of envenoming and deathsen_US
dc.typeArticleen_US
dc.identifier.departmentPublic Healthen_US
dc.identifier.departmentParasitologyen_US
dc.identifier.departmentMedicineen_US
dc.creator.corporateauthorPublic Library of Scienceen_US
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