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Title: | Factors associated with urinary tract infections caused by extended spectrum β-lactamase producing organisms (ESBL-UTI) among hospitalized patients in a tertiary care hospital |
Authors: | Fernando, S.C. Wickramasinghe, R.D.S.S. Luke, W.A.N.V. Gunathilake, M.P.M.L. Sebastiampillai, B.S. Miththinda, J.K.N.D. Silva, F.H.D.S. Premaratna, B.A.H.R. |
Keywords: | Urinary Tract Infections Urinary Tract Infections-microbiology beta-Lactamases Tertiary Care Centers |
Issue Date: | 2016 |
Publisher: | Sri Lanka Medical Association |
Citation: | Sri Lanka Medical Association, 129th Anniversary International Medical Congress. 2016: 183 |
Abstract: | INTRODUCTION AND OBJECTIVES: Management of infections caused by ESBL producers is a challenge and expensive. Known associations for ESBL-UTI include recent hospitalizations, recent treatment with cephalosporins, quinolones or penicillin, age over 60 years, male gender, diabetes mellitus, recent Klebsiella pneumoniae infection and obstructive uropathy. Associations for ESBL-UTI in Sri Lanka are not known. METHOD: In order to identify associations of urinary tract infections (UTIs) caused by ESBL producers (ESBL-UTI),a descriptive cross-sectional study was carried out in patients with culture positive ESBL-UTIs admitted to the Professorial Medical unit, Colombo North Teaching Hospital. Patients’ medical records and an interviewer administered questionnaire were used to obtain data. RESULTS: There were 61 patients, 30 (49.1%) males with a mean age of 64.1 years. Of them, 54 (88.5%) had diabetes mellitus,38 (62.2%) had hypertension and 10 (16.3%) had chronic liver disease (CLD). 21 (34.4%) had acute pyelonephritis, 19 (31.1%) had evidence of chronic kidney disease,8 (13%) had obstructive uropathy by ultrasonography. A history of constipation was given in 27 (44.2%), hospitalization during the past 3 months in 30 (49.2%), urinary catheterization in 20 (32.7%) and antibiotic treatment within the past 3 months in 39 (63.9%). CONCLUSION: Most associations for ESBL-UTI in Sri Lanka were similar to that had been previously described. However the observed higher incidence of CLD, hypertension and CKD needs further evaluation. The fact that 50.8% did not have a history of recent hospitalization and 36.1% did not have recent antibiotic therapy suggest high community prevalence of ESBL producing organisms. |
Description: | Poster Presentation Abstract (PP 57), 129th Anniversary International Medical Congress, Sri Lanka Medical Association, 25-27 July 2016 Colombo, Sri Lanka |
URI: | http://repository.kln.ac.lk/handle/123456789/17827 |
ISSN: | 0009-0895 |
Appears in Collections: | Conference Papers |
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