Please use this identifier to cite or link to this item: http://repository.kln.ac.lk/handle/123456789/17469
Title: The Effect of acyclovir on the acute and latent murine gammaherpesvirus-68 infection of mice
Authors: Sunil-Chandra, N.P.
Efstathiou, S.
Nash, A.A.
Issue Date: 1994
Publisher: Sage Publishing
Citation: Antiviral Chemistry and Chemotherapy. 1994; 5(6): 290-296
Abstract: Mice inoculated intranasally with murine gammaherpesvirus-68 were used to evaluate the efficacy of acyclovir (ACV) in the treatment of acute and latent infections. Effectiveness was measured by infectious virus assay of the lung (site of active replication) and infectious centre assay of spleen cells (site of latency). Intraperitoneal administration of ACV at 6-h intervals starting soon after inoculation was more effective in reducing infectious virus in the lung than was treatment with 12-hourly injections commencing 3 days post-infection.
URI: http://repository.kln.ac.lk/handle/123456789/17469
ISSN: 0956-3202 (Print)
2040-2066 (Electronic)
0956-3202 (Linking)
Appears in Collections:Journal/Magazine Articles

Files in This Item:
File Description SizeFormat 
Sunichandra-Antiviral ChemChemo-1994.pdf968.5 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.