Please use this identifier to cite or link to this item: http://repository.kln.ac.lk/handle/123456789/1711
Title: Treatment of lamivudine-resistant hepatitis B infection in post-renal transplant patients with Adefovir dipivoxil: preliminary results
Authors: de Silva, H.J.
Dassanayake, A.S.
Manamperi, A.
de Silva, A.P.
Issue Date: 2006
Publisher: Elsevier
Citation: Transplantation Proceedings. 2006; 38(9): 3118-120
Abstract: We report the treatment outcome in six post-renal transplant patients with lamivudine-resistant hepatitis B virus (LR-HBV) infection using adefovir dipivoxil and followed for 6 to 18 months. Posttransplant immunosuppressive therapy was not altered. Adefovir dipivoxil effectively suppressed hepatitis B virus DNA and improved alanine transferase, although DNA suppression seemed dependent on continued therapy. Nephrotoxicity led to withdrawal of the drug in three patients. This may limit therapeutic usefulness in a significant proportion of post-renal transplant patients with LR-HBV infection.
Description: Indexed in MEDLINE
URI: http://repository.kln.ac.lk/handle/123456789/1711
ISSN: 0041-1345 (Print)
1873-2623 (Electronic)
Appears in Collections:Journal/Magazine Articles

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