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Please use this identifier to cite or link to this item: http://repository.kln.ac.lk/handle/123456789/1701
Title: Hemoglobin E-[beta] Thalassemia: Progress Report from the International Study Group
Authors: Premawardhena, A.
de Silva, S.
Arambepola, M.
Olivieri, N. F.
Vichinsky, E. P.
Merson, L.
Muraco, G.
Allen, A.
Fisher, C.
Peto, T.
Weatherall, D. J.
Keywords: beta-Thalassemia
beta-Thalassemia-epidemiology
beta-Thalassemia-classification
beta-Thalassemia-genetics
beta-Thalassemia-blood
beta-Thalassemia-therapy
Sri Lanka-epidemiology
Hemoglobin E
Hemoglobin E-genetics
Issue Date: 2005
Publisher: Wiley-Blackwell
Citation: Annals of the New York Academy of Sciences. 2005; 1054: pp.33-9
Abstract: A long-term observational study of Hb E-beta-thalassemia in Sri Lanka is beginning to define some of the genetic and environmental factors that are responsible for its remarkable phenotypic variability. In this population there is a very small difference between the steady-state hemoglobin levels between the mild and severe phenotypes, and it has been possible to stop transfusion in many of those who have been on long-term treatment of this kind. These preliminary observations, made over the last 7 years, provide directions for future research into this increasingly important disease.
Description: Indexed in MEDLINE
URI: http://repository.kln.ac.lk/handle/123456789/1701
ISSN: 0077-8923 (Print)
1749-6632 (Electronic)
Appears in Collections:Journal/Magazine Articles

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