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http://repository.kln.ac.lk/handle/123456789/1683
Title: | Sequential studies on thyroid antibodies during pregnancy |
Authors: | Smyth, P.P. Wijeyaratne, C.N. Kaluarachi, W.N. Smith, D.F. Premawardena, L.D.K.E. Parkes, A.B. Jayasinghe, A. de Silva, D.G.H. Lazarus, J.H. |
Issue Date: | 2005 |
Publisher: | Mary Ann Liebert Publishers |
Citation: | Thyroid. 2005; 15(5): pp.474-7 |
Abstract: | Thyroid antibodies were measured sequentially in 25 pregnant women from a Sri Lankan population. A high prevalence of antithyroidantibodies, particularly antithyroglobulin antibodies (TgAb) had previously been demonstrated in female schoolchildren drawn from this population. In the present study TgAb were detected in 36.8% of nonpregnant controls while thyroid peroxidase antibody (TPOAb) positivity was present in 26.3%. The prevalence of both antibodies in the pregnancy study group showed a progressive decline compared to nonpregnant controls throughout gestation becoming undetectable in the third trimester. The results are consistent with an immunosuppressive effect of pregnancy in a population in whom high thyroid autoantibody titers may have resulted from a recent salt iodization program. |
Description: | Indexed in MEDLINE |
URI: | http://repository.kln.ac.lk/handle/123456789/1683 |
ISSN: | 1050-7256 (Print) 1557-9077 (Electronic) |
Appears in Collections: | Journal/Magazine Articles |
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