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Title: | Prevalence and intensity of Wuchereria bancrofti antigenaemia in Sri Lanka by Og4C3 ELISA using filter paper-absorbed whole blood |
Authors: | Weerasooriya, M.V. Gunawardena, N.K. Itoh, M. Qiu, X.G. Kimura, E. |
Keywords: | Filariasis Wuchereria bancrofti Filariasis-epidemiology Sri Lanka-epidemiology Wuchereria bancrofti-immunology Antigens, Helminth-blood Prevalence |
Issue Date: | 2002 |
Publisher: | Oxford University Press |
Citation: | Transactions of the Royal Society of Tropical Medicine and Hygiene. 2002; 96(1): pp. 41-45 |
Abstract: | In Sri Lanka 2741 people from Matara, an endemic area for Wuchereria bancrofti, were examined in 1996/97 for microfilariae by 60-microL blood smear and for circulating filarial antigens by Og4C3 ELISA using filter paper-absorbed whole blood. The overall prevalence of microfilaraemia was 3.4%, and that of antigenaemia 14.4%. The prevalence of antigen-positive and microfilaria-negative people was 11.3%. Analysed by age-group,antigenaemia prevalence was similar in all groups, and the average number of antigen units was already very high in the age-group < 10 years, indicating that the infection started in early childhood. Among those who were antigen positive, the microfilaria prevalence was lower in females than in males. Diethylcarbamazine treatment eliminated microfilariae in 78% of the positives. However, 17 months after the treatment, antigenaemia was still positive in 76% of those who were parasitologically cured. |
Description: | Indexed in MEDLINE |
URI: | http://repository.kln.ac.lk/handle/123456789/1540 |
ISSN: | 0035-9203 (Print) 1878-3503 (Electronic) |
Appears in Collections: | Journal/Magazine Articles |
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