Please use this identifier to cite or link to this item: http://repository.kln.ac.lk/handle/123456789/1540
Title: Prevalence and intensity of Wuchereria bancrofti antigenaemia in Sri Lanka by Og4C3 ELISA using filter paper-absorbed whole blood
Authors: Weerasooriya, M.V.
Gunawardena, N.K.
Itoh, M.
Qiu, X.G.
Kimura, E.
Keywords: Filariasis
Wuchereria bancrofti
Filariasis-epidemiology
Sri Lanka-epidemiology
Wuchereria bancrofti-immunology
Antigens, Helminth-blood
Prevalence
Issue Date: 2002
Publisher: Oxford University Press
Citation: Transactions of the Royal Society of Tropical Medicine and Hygiene. 2002; 96(1): pp. 41-45
Abstract: In Sri Lanka 2741 people from Matara, an endemic area for Wuchereria bancrofti, were examined in 1996/97 for microfilariae by 60-microL blood smear and for circulating filarial antigens by Og4C3 ELISA using filter paper-absorbed whole blood. The overall prevalence of microfilaraemia was 3.4%, and that of antigenaemia 14.4%. The prevalence of antigen-positive and microfilaria-negative people was 11.3%. Analysed by age-group,antigenaemia prevalence was similar in all groups, and the average number of antigen units was already very high in the age-group < 10 years, indicating that the infection started in early childhood. Among those who were antigen positive, the microfilaria prevalence was lower in females than in males. Diethylcarbamazine treatment eliminated microfilariae in 78% of the positives. However, 17 months after the treatment, antigenaemia was still positive in 76% of those who were parasitologically cured.
Description: Indexed in MEDLINE
URI: http://repository.kln.ac.lk/handle/123456789/1540
ISSN: 0035-9203 (Print)
1878-3503 (Electronic)
Appears in Collections:Journal/Magazine Articles

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