Please use this identifier to cite or link to this item:
http://repository.kln.ac.lk/handle/123456789/13718
Title: | The prevalence of upper respiratory symptoms in a cohort of adults presenting with symptoms of gastro-oesophageal reflux disease |
Authors: | Amarasiri, D.L. Pathmeswaran, A. Dassanayake, A.S. de Silva, A.P. Adikari, M.D.B. Sanjeewa, P.A.B. Jayaratne, A. de Silva, H.J. |
Keywords: | Respiratory Tract Diseases Gastroesophageal Reflux Prevalence |
Issue Date: | 2016 |
Publisher: | Sri Lanka Medical Association |
Citation: | The Ceylon Medical Journal. 2016; 61(2): 63–67 |
Abstract: | INTRODUCTION: Gastro-oesophageal reflux disease (GORD) is the pathological reflux of gastric contents into the oesophagus. The oesophagus and the upper respiratory tract have a common origin from the foregut. There is increasing evidence for multiple associations of GORD with the upper respiratory tract. OBJECTIVES: To study the presence of and association of upper respiratory symptoms (URS) with GORD. METHODS: Seventy adults scoring ≥12.5 on a previously validated GORD symptom score (GORD patients) and 70 healthy controls who had infrequent GORD symptoms or no upper gastro-intestinal complaints completed a pre-tested URS questionnaire on the frequency of 14 URS in 5 categories (laryngeal, nasal, pharyngeal, sinusal and aural). All GORD patients underwent upper gastro-intestinal endoscopy. The calculated URS score was correlated against the GORD symptom score and endoscopy findings. RESULTS: URS scores and individual symptom scores were higher in GORD patients compared to controls (mean ± SE, 4.7 ± 4.0; 1.9 ± 2.3). Individuals with higher GORD symptom scores reported more frequent URS. Pharyngeal symptoms had the highest correlation with the GORD symptom score (r=0.507, p<0.001). The presence of oeso-phagitis did not seem to influence the frequency of reporting URS. CONCLUSION: Upper respiratory symptoms are common in individuals with GORD symptoms though there appears to be no association with oesophageal mucosal damage. |
URI: | http://repository.kln.ac.lk/handle/123456789/13718 |
ISSN: | 2386-1274 |
Appears in Collections: | Journal/Magazine Articles |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
8301-29146-2-PB.pdf | 52.39 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.