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Title: | Chronic low dose FSH in polycystic ovarian syndrome and related anovulatory states |
Authors: | Yong, F. L. Ng, S. C. Chan, C. Kumar, J. Ratnam, S. Pathiraja, R. P. |
Keywords: | Polycystic Ovary Syndrome FSH-Therapeutic use Gonadotropins-therapy |
Issue Date: | 1998 |
Publisher: | Sri Lanka College of Obstetricians and Gynaecologists |
Citation: | Sri Lanka Journal of Obstetrics and Gynaecology.1998; 20: pp.28-33 |
Abstract: | Objective: To compare the response to gonadotrophin therapy in patients having polycystic ovarian syndrome (PCOS) with those having a similar syndrome (PCOS like). Design: prospective cohort study. Setting: National University Hospital, Singapore. Patients: PCOS subjects (n=25, 51 cycles) having infertility , amnorrhoealoligomenorrhoea, ultra- sound evidence of PCOS, reversed LH: FSH and high serum testosterone. PCOS like subjects (n=40, 59 cycles) having at least one but not all the fea- tures of PCOS. Intervention: Chronic low dose intramuscular (im) follicular stimulating Hormone (FSH) Mean outcome measures: Total dose of FSH used, number of days of the stimulation, peak oestradiol (EJ levels, number of mature (17mm) and intermediate (10-16 mm) follicles, hyperstimulation, premature ovulation, miscarriage and pregnancy rates. Results: PCOS subjects required higher doses of FSH X=29 sd 17 V s X=21. 8 se 20.2 ampoules, p0.05 and longer duration of therapy X |
URI: | http://repository.kln.ac.lk/handle/123456789/1364 |
ISSN: | 1391-7536 (Print) 2279-1655 (Online) |
Appears in Collections: | Journal/Magazine Articles |
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