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DC Field | Value | Language |
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dc.contributor.author | de Silva, D.G.H. | en_US |
dc.contributor.author | Candy, D.C. | en_US |
dc.contributor.author | Mendis, L.N. | en_US |
dc.contributor.author | Chart, H. | en_US |
dc.contributor.author | Rowe, B. | en_US |
dc.date.accessioned | 2014-10-29T09:10:33Z | - |
dc.date.available | 2014-10-29T09:10:33Z | - |
dc.date.issued | 1992 | en_US |
dc.identifier.citation | The Journal of Infection. 1992; 25(3): pp.273-278 | en_US |
dc.identifier.issn | 0163-4453 (Print) | en_US |
dc.identifier.issn | 1532-2742 (Electronic) | en_US |
dc.identifier.uri | http://repository.kln.ac.lk/handle/123456789/1167 | - |
dc.description | Indexed in MEDLINE | - |
dc.description.abstract | A total of 192 samples of serum from 113 Sri Lankan patients with clinical dysentery was examined for antibodies of the IgM class to the lipopolysaccharides (LPSs) of Shigella dysenteriae-1 and Escherichia coli O157:H7. By means of ELISA and immunoblotting, 59 patients were found to have serum antibodies to the LPS of S. dysenteriae-1 only. Four samples from one patient were found to contain serum antibodies to the LPSs of both S. dysenteriae-1 and E. coli O157:H7. Antibodies to the LPS of S. dysenteriae-1 were also detected in 16 samples from 25 children, from Sri Lanka, with no previous history of dysentery; one of these children also had antibodies to the LPS of E. coli O157:H7. Analysis of 16 samples from apparently healthy children in the U.K. showed that only one serum contained antibodies to the LPS of S. dysenteriae-1. This patient had a history of recent travel to Pakistan. The isolation of S. dysenteriae-1 remains the preferred test for the diagnosis of bacillary dysentery. The use of serology as a means of providing evidence of infection with S. dysenteriae-1, however may prove to be a useful adjunct to cultural techniques but needs to be validated in an area where this organism is endemic | en_US |
dc.publisher | Elsevier-W.B. Saunders | en_US |
dc.subject | Shigella dysenteriae | - |
dc.subject | Shigella dysenteriae-classification | - |
dc.subject | Dysentery, Bacillary-diagnosis | - |
dc.subject | Electrophoresis, Polyacrylamide Gel | - |
dc.subject | Enzyme-Linked Immunosorbent Assay | - |
dc.subject | Escherichia coli-isolation and purification | - |
dc.subject | Immunoglobulin M-immunology | - |
dc.subject | Lipopolysaccharides-immunology | - |
dc.title | Serological diagnosis of infection by Shigella dysenteriae-1 in patients with bacillary dysentery. | en_US |
dc.type | Article | en_US |
dc.identifier.department | Paediatrics | en_US |
dc.creator.corporateauthor | British Society for the Study of Infection | en_US |
Appears in Collections: | Journal/Magazine Articles |
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