Evaluation of the efficacy of Melothria maderaspatana in the alleviation of carbon tetrachloride-induced liver dysfunction

Please use this identifier to cite or link to this item: http://repository.kln.ac.lk/handle/123456789/1116

Title:	Evaluation of the efficacy of Melothria maderaspatana in the alleviation of carbon tetrachloride-induced liver dysfunction
Authors:	Thabrew, M.I. Jayathilake, K.A. Perera, D.J.
Keywords:	Carbon Tetrachloride Poisoning Carbon Tetrachloride Poisoning-drug therapy Drug-Induced Liver Injury Drug-Induced Liver Injury-drug therapy Plant Extracts Plant Extracts-therapeutic use
Issue Date:	1988
Publisher:	Elsevier
Citation:	Journal of Ethnopharmacology. 1988; 23(2-3): pp.305-312
Abstract:	An investigation was carried out to evaluate the ability of Melothria maderaspatana to protect the livers of albino rats from carbon tetrachloride-mediated alterations in liver histopathology and serum levels of alanine aminotransferase, aspartate aminotransferase and alkaline phosphatase. Treatment with an aqueous extract of Melothria aerial parts (either before or after CCl4 administration) markedly decreased CCl4-mediated alterations in liver histopathology as well as serum enzyme levels. Results provide supportive evidence for the folklore view that this plant is a good hepatotonic
Description:	Indexed in MEDLINE
URI:	http://repository.kln.ac.lk/handle/123456789/1116
ISSN:	0378-8741 (Print) 1872-7573 (Electronic)
Appears in Collections:	Journal/Magazine Articles

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