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DC Field | Value | Language |
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dc.contributor.author | Amarasiri, L | en_US |
dc.contributor.author | Pathmeswaran, A. | en_US |
dc.contributor.author | Ranasinghe, C. | en_US |
dc.contributor.author | de Silva, H.J. | en_US |
dc.date.accessioned | 2015-12-24T22:03:05Z | en_US |
dc.date.available | 2015-12-24T22:03:05Z | en_US |
dc.date.issued | 2006 | en_US |
dc.identifier.citation | Journal of Gastroenterology and Hepatology. 2006; 21(Suppl 6): A381 | en_US |
dc.identifier.issn | 0815-9319 (Print) | en_US |
dc.identifier.issn | 1440-1746 (Electronic) | en_US |
dc.identifier.uri | http://repository.kln.ac.lk/handle/123456789/10956 | en_US |
dc.description | Poster Session Abstract (No.27), 16th Asian Pacific Digestive Week, November 26–29, 2006, Lahug Cebu City, Philippines | en_US |
dc.description.abstract | BACKGROUND: The prevalence of GERD is increasing worldwide. Community prevalence in Sri Lanka is unknown. OBJECTIVES: To develop a clinical score to screen for GERD in the community and assess whether a score using symptom frequency and severity correlates better to an objective measure of GERD than one using only symptom frequency. METHODS: A cross-sectional validity study carried out on 72 patients (endoscopy positive) and 75 controls (comparable in age and gender). All faced a GERD-specific interviewer-administered questionnaire assessing seven upper gastro-intestinal symptoms, each graded for frequency (4- items) and severity (5-items). Two scores were generated. Score 1: sum of frequency of symptoms and score 2: sum of products of frequency and severity of each symptom. All patients underwent 24 h pH-metry. Validity established by correlating symptom scores with 24 h pH-metry parameters. Cut-off values determined by receiver-operating characteristic curves. RESULTS: Mean scores of cases were significantly higher than controls (p < 0.001). Cut-off score for score 1 was ≥11.50 (sensitivity 91.7%, speci- ficity 82.7%, positive and negative predictive values 70.0% and 95.9%). Cut-off score for score 2 was ≥14.50 (sensitivity 94.4%, specificity 78.7%, positive and negative predictive values 66.0% and 97.0%). Both scores showed high reproducibility (intra-class correlation coefficient of score 1 = 0.95 and score 2 = 0.89). There was good correlation between symptom scores and 24-h pH parameters (Spearman rank correlation, p = 0.01), but score 2 showed a significantly better correlation. CONCLUSIONS: Our GERD questionnaire is valid, reproducible, with better correlation with an objective test when both severity and frequency of symptoms were scored | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Wiley Blackwell Scientific Publications | en_US |
dc.subject | Gastroesophageal Reflux-epidemiology | en_US |
dc.subject | Gastroesophageal Reflux | en_US |
dc.subject | Prevalence | en_US |
dc.subject | Validation Studies | en_US |
dc.title | Validation of a clinical scoring system to detect gastro-oesophageal reflux disease (GERD) in epidemiological surveys | en_US |
dc.type | Conference Abstract | en_US |
dc.creator.corporateauthor | Asian Pacific Association of Gastroenterology | en |
dc.creator.corporateauthor | Asian Pacific Association for the Study of the Liver | en |
Appears in Collections: | Conference Papers |
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