Please use this identifier to cite or link to this item: http://repository.kln.ac.lk/handle/123456789/10942
Title: Upper respiratory symptoms are common in a cohort of patients with symptomatic gastrooesophageal reflux disease (GORD) in Sri Lanka
Authors: Amarasiri, D.L.
Adikari, D.
Sanjeewa, B.
Jayaratne, A.
Dassanayake, A.S.
de Silva, A.P.
de Silva, H.J.
Keywords: Gastroesophageal Reflux
Respiratory Tract Infections
Issue Date: 2011
Publisher: Wiley Blackwell Scientific Publications
Citation: Journal of Gastroenterology and Hepatology. 2011; 26(Suppl 5):201
Abstract: INTRODUCTION: There is increasing evidence for multiple associations between gastro-oesophageal reflux disease (GORD) and the upper respiratory tract. This study evaluated the presence of upper respiratory symptoms (URS) in a cohort of patients with GORD symptoms from Sri Lanka. METHOD: Seventy adults scoring ≥12.5 on a previously validated GORD symptom score (GORD patients) and 70 healthy controls who had infrequent or no GORD symptoms completed a pre-tested, valid URS questionnaire. They were questioned on frequency of 14 URS in 5 categories (laryngeal, nasal, pharyngeal, sinusal and aural). All GORD patients underwent gastroscopy. An URS score was calculated and correlated against the GORD symptom score and gastroscopy fi ndings. RESULTS : The GORD patients (median age (range) 36 (15–65); 38% males) and controls (median age (range) 38 (15–68); 38% males) were comparable. URS scores were higher in GORD patients (mean ± SE, 4.7 ± 4.0) compared to controls (mean ± SE, 1.9 ± 2.3), as were individual symptom scores. Individuals with higher GORD symptoms scores reported more frequent URS. Nasal symptoms had the highest correlation with the GORD symptom score (r = 0.410; P = 0.001). of the GORD patients, 42 had no evidence of oesophageal or gastric mucosal damage. 28 had evidence of refl ux oesophagitis. In them, the presence of oesophagitis did not seem to influence the frequency of reporting URS. CONCLUSION : URS are common in individuals with GORD symptoms though there appears to be no association with oesophageal mucosal damage
Description: Poster Session Abstract (P281), 21st Asian Pacific Digestive Week 2011 , October 1–4, 2011, SUNTEC Singapore International Convention & Exhibition Centre, Singapore
URI: http://repository.kln.ac.lk/handle/123456789/10942
ISSN: 0815-9319 (Print)
1440-1746 (Electronic)
Appears in Collections:Conference Papers

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