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DC Field | Value | Language |
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dc.contributor.author | Devanarayana, N.M. | |
dc.contributor.author | Rajindrajith, S. | |
dc.date.accessioned | 2015-12-24T02:13:29Z | |
dc.date.available | 2015-12-24T02:13:29Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Proceedings of the European Pediatric Gastrointestinal Motility Meeting. 2013; 6 :53 | en_US |
dc.identifier.uri | http://repository.kln.ac.lk/handle/123456789/10941 | |
dc.description | Poster Session Abstract(P33) Proceedings of 6th European Pediatric Gastrointestinal Motility Meeting, October 3–5, 2013, Brussels, Belgium . | en_US |
dc.description.abstract | AJMS; Cyclical vomiting syndrome (CVS) is an uncommon, but bothersome upper gastrointestinal disorder seen in ap- roximately 0.5% of school aged children. Pathophysiology of this disorder is not fully understood. The aim of this study was to evaluate the gastric motility in children with CVS. METHODS : Consecutive 12 children [6 (50.0%) males, age 4-15years, mean 8.5 years, SD 3.2 years) referred to Gastro-nterology Research Laboratory, Faculty of Medicine, University of Kelaniya, Sri Lanka, from January 2008'to December2012, were screened and those fulfilling Rome HI criteria for CVS were recruited. None-had clinical or laboratory vidence of organic disorders or other gastrointestinal disorders. Twenty healthy children were recruited as controls [8 (40%) males, age 4-14 years, mean 8.4 years, SD 3.0 years]. Fasting antral area (FAA), liquid gastric emptying rate GER) and antral motility parameters were assessed using a well-established and validated ultrasound method, RESULTS: Average GER (38.2% vs. 66.2%, in controls), amplitude of antral contractions (51.1% vs. 89%) and antral -lotuty index (4.6 vs. 8.3) were lower and FAA (1.6cm2 vs. 0.6cm2) was higher in patients with CVS (p < 0.0001). Fre-uency of antral contractions (8.8 vs. 9.3) did not show a significant difference (p - 0.07). Scores obtained for severity )f abdominal pain had a negative correlation with GER (r = -0.25, p < 0,0001), amplitude of antral contractions (r = ;030,/5 < 0.0001) and motility index (r = -0.30,;p < 0,0001). A positive correlations were observed between FAA and severity(r= 0.18,p = 0.007). CONCLUSIONS : Gastric emptying rates and antral motility parameters are impaired in children with CVS. Furthermore, we 3served a significant correlation between symptom severity and gastric motility. These findings are suggestive of gastric lotility abnormalities in pathogenesis of CVS. | en_US |
dc.description.sponsorship | European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Belgian Society of Paediatric Gastroenterology, Hepatology and Nutrition (BeSPGHAN), | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Belgian Society of Paediatric Gastroenterology, Hepatology and Nutrition (BeSPGHAN), | en_US |
dc.subject | Gastrointestinal Motility | en_US |
dc.subject | Gastrointestinal Diseases | en_US |
dc.subject | Child | en_US |
dc.subject | Adolescent | en_US |
dc.subject | Familial cyclic vomiting syndrome | en_US |
dc.subject | Vomiting | en_US |
dc.title | Gastric motility abnormalities in children suffering from cyclical vomiting syndrome | en_US |
dc.type | Conference Abstract | en_US |
Appears in Collections: | Conference Papers |
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