Evaluation of the efficacy of Melothria maderaspatana in the alleviation of carbon tetrachloride-induced liver dysfunction

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dc.contributor.authorThabrew, M.I.en_US
dc.contributor.authorJayathilake, K.A.en_US
dc.contributor.authorPerera, D.J.en_US
dc.creator.corporateauthorInternational Society for Ethnopharmacologyen_US
dc.date.accessioned2014-10-29T09:09:58Z
dc.date.available2014-10-29T09:09:58Z
dc.date.issued1988en_US
dc.descriptionIndexed in MEDLINE
dc.description.abstractAn investigation was carried out to evaluate the ability of Melothria maderaspatana to protect the livers of albino rats from carbon tetrachloride-mediated alterations in liver histopathology and serum levels of alanine aminotransferase, aspartate aminotransferase and alkaline phosphatase. Treatment with an aqueous extract of Melothria aerial parts (either before or after CCl4 administration) markedly decreased CCl4-mediated alterations in liver histopathology as well as serum enzyme levels. Results provide supportive evidence for the folklore view that this plant is a good hepatotonic
dc.identifier.citationJournal of Ethnopharmacology. 1988; 23(2-3): pp.305-312en_US
dc.identifier.departmentBiochemistryen_US
dc.identifier.issn0378-8741 (Print)en_US
dc.identifier.issn1872-7573 (Electronic)en_US
dc.identifier.urihttp://repository.kln.ac.lk/handle/123456789/1116
dc.publisherElsevieren_US
dc.subjectCarbon Tetrachloride Poisoning
dc.subjectCarbon Tetrachloride Poisoning-drug therapy
dc.subjectDrug-Induced Liver Injury
dc.subjectDrug-Induced Liver Injury-drug therapy
dc.subjectPlant Extracts
dc.subjectPlant Extracts-therapeutic use
dc.titleEvaluation of the efficacy of Melothria maderaspatana in the alleviation of carbon tetrachloride-induced liver dysfunctionen_US
dc.typeArticleen_US

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