Clostridium difficile infection in inflammatory bowel disease patients in Sri Lanka

dc.contributor.authorWaraketiya, P.R.
dc.contributor.authorde Silva, A.P.
dc.contributor.authorWijesinghe, N.T.
dc.contributor.authorWaraketiya, P.R.
dc.contributor.authorWijewantha, H.S.
dc.contributor.authorChandrasena, L.G.
dc.contributor.authorPathmeswaran, A.
dc.contributor.authorde Silva, H.J.
dc.date.accessioned2016-04-01T08:23:08Z
dc.date.available2016-04-01T08:23:08Z
dc.date.issued2012
dc.descriptionPoster Presentation Abstract (PP 163), 125th Anniversary Scientific Medical Congress, Sri Lanka Medical Association, June 2012 Colombo, Sri Lankaen_US
dc.description.abstractINTRODUCTION: Over the last decade an increase in Clostridium difficile associated diarrhoea (CDAD) has been observed among Caucasians (1%). The frequency of CDAD is very high in Caucasian IBD patients; 8.7% in one study of IBD patients in remission. This has led to guidelines recommending routine screening for CDAD in IBD. Clinical impressions are that CDAD is rare among Sri Lankans. AIMS: This study was conducted to determine the frequency of CDAD in a cohort of Sri Lankan IBD patients and healthy controls. METHODS: Cases [n=154] were histologically confirmed IBD patients, in clinical remission. The controls [n=100) were non-IBD patients who presented to medical clinics without diarrhoea and with no exposure to antibiotics for up to 8 weeks prior to recruitment. Immunoassays for Clostridium difficile toxins A and B were performed on stool samples obtained from both groups. RESULTS: The frequency of CDAD was 0.7% (n=l) and 0% (n=0) in IBD patients and controls respectively. CONCLUSIONS: Compared to Caucasians, CDAD was very rare in this cohort of Sri Lankans, including those with IBD. Routine screening for CDAD does not seem necessary in our setting.en_US
dc.identifier.citationSri Lanka Medical Association, 125th International Medical Congress. 2012;57 Suppliment1: 150en_US
dc.identifier.issn0009-0895
dc.identifier.urihttp://repository.kln.ac.lk/handle/123456789/12427
dc.language.isoen_USen_US
dc.publisherSri Lanka Medical Associationen_US
dc.subjectClostridium difficile infectionen_US
dc.titleClostridium difficile infection in inflammatory bowel disease patients in Sri Lankaen_US
dc.typeArticleen_US

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