A Comprehensive Review of The Chemical Composition and Pharmacological Activities of The Genus Dialium

Abstract

The Dialium genus consists of about 35 recognized species found in tropical regions, which are flowering plants of Leguminosae. However, only a few of the several species in this genus, including D. angolense, D. cochinchinense, D. corbisieri, D. dinklagei, D. excelsum, D. guineense, D. indum, D. ovoideum thwaites, and D. packyphyllum have been the focus of investigation. Traditional systems of medicine are also well aware of the therapeutic benefits of the Dialium genus. Many researchers have investigated the species for its pharmacological properties and medicinal uses, such as antioxidant, anti-microbial, anti-plasmodial, cytotoxic and anti-hepatotoxic, anti-diabetic and anti-inflammatory activities. This report aims to review the recent studies on phytochemistry, pharmacological applications, bioactive compound isolation and identification of the Dialium genus. Thus, the search for reliable therapeutic drugs to address current medical problems led to the development of novel bioresources that met the requirements of researchers.