| dc.description.abstract |
Pharmacognostical study revealed that the ingredients of Amalakayas Rasayana are authentic.
Physicochemical parameters of AR are within the accepted range. The 30.6% w/w of total ash and acid
insoluble ash 3.45% w/w may be due to its iron (Fe2
O3
) content. AR contains 50% w/w water soluble
extractives, which indicates that AR is easily soluble in water. AR gives 2 and 6 spots on short and long UV
light respectively, which indicate that its chemical compounds are easily separable. AR contains 27.5% w/
w iron (Fe2
O3
) indicating it?s a good source of iron. The total phenolic content was given satisfactory linearity
against Gallic acid equivalents (R2
= 0.998). The DPPH (R2
=1 in polynomial plotting) assay showed good
linearity against ascorbic acid indicating its free radical scavenging activity. EDTA & NBT assays showed
sufficient linearity (R? = 0.976) against ascorbic acid indicating potent superoxide radical scavenging activity,
whereas ferrous reducing power was also showed satisfactory linearity (R? = 0.986). Total tannin was
estimated 2.82 % w/w. The extract was also showed ROS scavenging activities (R2
=0.976; EC50=77.5?g/ml).
These pharmacognostical, physic-chemical and analytical parameters will help to establish further standards
of Ayurvedic drugs to assure their safety, purity and efficacy. |
en_US |