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Antibacterial polyketide from Lasiodiplodia theobromae, inhabiting the lichen host, Pyrenula bahiana on mangrove ecosystems in Puttalam lagoon, Sri Lanka

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dc.contributor.author Paranagama, P. A.
dc.contributor.author Santhirasegaram, S.
dc.contributor.author Fathima, M. M. A.
dc.contributor.author Wickramarachchi, S. R.
dc.contributor.author Attanayake, R. N.
dc.contributor.author Weerakoon, G.
dc.contributor.author Maduranga, K.
dc.date.accessioned 2022-10-12T06:52:23Z
dc.date.available 2022-10-12T06:52:23Z
dc.date.issued 2022
dc.identifier.citation Paranagama, P. A.,Santhirasegaram, S.,Fathima, M. M. A.,Wickramarachchi, S. R.,Attanayake, R. N.,Weerakoon, G. and Maduranga, K.(2022), Antibacterial polyketide from Lasiodiplodia theobromae, inhabiting the lichen host, Pyrenula bahiana on mangrove ecosystems in Puttalam lagoon, Sri Lanka.Asian Journal of Chemistry en_US
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/25301
dc.description.abstract Lasiodiplodia theobromae is one of the frequently isolated fast growing endolichenic fungus. This fungus was isolated from the lichen host, Pyrenula bahiana collected from the mangrove ecosystems in Puttlam lagoon and identity was confirmed based on rDNA-ITS sequence homology. Secondary metabolites of L. theobromae were extracted into ethyl acetate and subjected to antibacterial assay against Escherichia coli (ATCC25922), Staphylococcus aureus (ATCC25923) and Bacillus subtilis (ATCC6051). Crude extract at a concentration of 6.8 μg/ml showed good anti-bacterial activity against the bacterial strain S. aureus compared with the activity of the standard Azithromycin at a concentration of 5.0 μg/ml. Active crude extract was partitioned to obtain methanol, en_US
dc.publisher Asian Journal of Chemistry en_US
dc.title Antibacterial polyketide from Lasiodiplodia theobromae, inhabiting the lichen host, Pyrenula bahiana on mangrove ecosystems in Puttalam lagoon, Sri Lanka en_US


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