dc.contributor.author |
Devanarayana, N.M. |
en_US |
dc.contributor.author |
Rajindrajith, S. |
en_US |
dc.date.accessioned |
2014-10-29T09:32:05Z |
|
dc.date.available |
2014-10-29T09:32:05Z |
|
dc.date.issued |
2010 |
en_US |
dc.identifier.citation |
Journal of Tropical Pediatrics. 2010; 56(3): 144-8 |
en_US |
dc.identifier.issn |
0142-6338 (Print) |
en_US |
dc.identifier.issn |
1465-3664 (Electronic) |
en_US |
dc.identifier.uri |
http://repository.kln.ac.lk/handle/123456789/2010 |
|
dc.description |
Indexed in MEDLINE |
|
dc.description.abstract |
Emotional stress is associated with some functional gastrointestinal diseases, but its role in aetiology of functional constipation is unclear. This island-wide, questionnaire-based, cross-sectional survey was conducted to assess the association between constipation and emotional stress, in 10-16-year-olds. Constipation was defined using Rome III criteria. Out of 2699 children included in the analysis, 416 (15.4%) had constipation. Constipation was higher in those exposed to stressful events (odds ratio 2.52, p < 0.0001). Separation from the best friend, failure in an examination, severe illness of a family member, loss of job by a parent, frequent punishment by parents and living in an area affected by separatist war remained independently associated with constipation (p < 0.05). In conclusion, constipation was significantly higher in children exposed to stressful life events. Modulation of gut motility through brain-gut axis probably alters colonic transit and ano-rectal functions, causing constipation. |
|
dc.publisher |
Oxford University Press |
en_US |
dc.title |
Association between constipation and stressful life events in a cohort of Sri Lankan children and adolescents |
en_US |
dc.type |
Article |
en_US |
dc.identifier.department |
Physiology |
en_US |
dc.identifier.department |
Paediatrics |
en_US |
dc.creator.corporateauthor |
University of California Los Angeles Division of Population Family and International Health |
en_US |
dc.creator.corporateauthor |
British Postgraduate Medical Federation Tropical Child Health Unit |
en_US |