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Association between constipation and stressful life events in a cohort of Sri Lankan children and adolescents

Show simple item record Devanarayana, N.M. en_US Rajindrajith, S. en_US 2014-10-29T09:32:05Z 2014-10-29T09:32:05Z 2010 en_US
dc.identifier.citation Journal of Tropical Pediatrics. 2010; 56(3): 144-8 en_US
dc.identifier.issn 0142-6338 (Print) en_US
dc.identifier.issn 1465-3664 (Electronic) en_US
dc.description Indexed in MEDLINE
dc.description.abstract Emotional stress is associated with some functional gastrointestinal diseases, but its role in aetiology of functional constipation is unclear. This island-wide, questionnaire-based, cross-sectional survey was conducted to assess the association between constipation and emotional stress, in 10-16-year-olds. Constipation was defined using Rome III criteria. Out of 2699 children included in the analysis, 416 (15.4%) had constipation. Constipation was higher in those exposed to stressful events (odds ratio 2.52, p < 0.0001). Separation from the best friend, failure in an examination, severe illness of a family member, loss of job by a parent, frequent punishment by parents and living in an area affected by separatist war remained independently associated with constipation (p < 0.05). In conclusion, constipation was significantly higher in children exposed to stressful life events. Modulation of gut motility through brain-gut axis probably alters colonic transit and ano-rectal functions, causing constipation.
dc.publisher Oxford University Press en_US
dc.title Association between constipation and stressful life events in a cohort of Sri Lankan children and adolescents en_US
dc.type Article en_US
dc.identifier.department Physiology en_US
dc.identifier.department Paediatrics en_US
dc.creator.corporateauthor University of California Los Angeles Division of Population Family and International Health en_US
dc.creator.corporateauthor British Postgraduate Medical Federation Tropical Child Health Unit en_US

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