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Host gene expression analysis in Sri Lankan melioidosis patients.

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dc.contributor.author Krishnananthasivam, S.
dc.contributor.author Jayathilaka, N.
dc.contributor.author Sathkumara, H.D.
dc.contributor.author Corea, E.
dc.contributor.author Natesan, M.
dc.contributor.author De Silva, A.D.
dc.date.accessioned 2017-12-13T09:33:40Z
dc.date.available 2017-12-13T09:33:40Z
dc.date.issued 2017
dc.identifier.citation Krishnananthasivam,S., Jayathilaka,N., Sathkumara,H.D., Corea,E., Natesan,M., De Silva,A.D. (2017) Host gene expression analysis in Sri Lankan melioidosis patients. PLoS Negl Trop Dis 11(6): e0005643. https://doi.org/10.1371/journal.pntd.0005643 en_US
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/18543
dc.description.abstract Melioidosis is a life threatening infectious disease caused by the gram-negative bacillus Burkholderia pseudomallei predominantly found in southeast Asia and northern Australia. Studying the host transcription profiles in response to infection is crucial for understanding disease pathogenesis and correlates of disease severity, which may help improve therapeutic intervention and survival. The aim of this study was to analyze gene expression levels of human host factors in melioidosis patients and establish useful correlation with disease biomarkers, compared to healthy individuals and patients with sepsis caused by other pathogens. en_US
dc.language.iso en en_US
dc.publisher PLoS Negl Trop Dis 11(6) en_US
dc.subject Host gene en_US
dc.subject melioidosis patients en_US
dc.subject pathogens en_US
dc.subject bacillus Burkholderia pseudomallei en_US
dc.title Host gene expression analysis in Sri Lankan melioidosis patients. en_US
dc.type Article en_US


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