International Postgraduate Research Conference (IPRC)
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Item Possible Application of Sickling Test in Haemoglobinopathy Screening of Sri Lanka.(19th Conference on Postgraduate Research, International Postgraduate Research Conference 2018, Faculty of Graduate Studies,University of Kelaniya, Sri Lanka, 2018) Darshana, T.; Perera, N.; Manamperi, A.; Premawardhena, A.The national screening programme for thalassaemia in Sri Lanka is currently using Full blood count (FBC) with red cell indices as the technique to identify haemoglobinopathies. This approach is likely to miss sickle haemoglobin (Hb-S) as it is well known that Hb-S is not associated with hypochromic microcytosis. Sickling test is a low cost microscopic screening test which detects sickle cell by its characteristic appearance. Therefore, the present study was undertaken to assess the performance of sickling test in identifying Hb-S among relatively high risk population in Hambantota district. A total of 581 school children (grade 11) were selected randomly from 5 schools in Hambantota district. 2 ml of EDTA blood sample was collected from each participant after obtaining informed assent and consent. Screening panel comprises with sickling test by sodium metabisulphite method, one tube osmotic fragility test, dichlorophenol indophenol test (DCIP), FBC and Zinc protoporphyrin test (ZPP). Haemoglobinphenotyping of each sample was confirmed by capillary electrophoresis technique. Four students out of 581 had sickle trait. Three other types of haemoglobinopathies were detected including β-thalassaemia trait (n=17), haemoglobin D trait (n=2) and haemoglobin E trait (n=1). 8% (n=44) had iron deficiency. All 4 cases with sickle trait were positive for sickling test and all other cases were negative. None of the Hb-S case demonstrated hypochromic microcytosis in FBC.The average time taken for red cells with Hb-S to assume the characteristic sickle shape was 28 minutes and 45 seconds. Sickling test demonstrated 100 % sensitivity and 100 % specificity in identifying sickle trait. Our results indicate depending solely on haemoglobin level and red cell indices is inappropriate since all of the sickle trait individuals would have been missed if sickling test was not done. Hence, the adaptation of sickling test can be recommended along with the Full Blood Count test when screening individuals for haemoglobinopathies in Sri LankaItem Prevalence of Personality Disorders in Late Adolescents with Drug Abuse(Faculty of Graduate Studies, University of Kelaniya, Sri Lanka, 2016) Perera, N.The world Health Organization defines health as “a state of complete physical, mental and social well-being, and not merely the absence of disease”. According to American Academy of Child and Adolescent’s Facts for Families, Late Adolescence is approximately between 19–21 years of age. Adolescence is a transitional stage of physical and psychological human development that generally occurs during the period from puberty to legal adulthood. In the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders, personality disorders are placed on Axis-ii in the multi axial scheme and defined through a set of general diagnostic criteria. Drug abuse is a chronic, often relapsing brain disease that causes compulsive drug seeking and use, despite harmful consequences to the addicted individual and to those around him or her. Research problem of the study was to search whether there is a prevalence of personality disorder in late adolescence with drug abuse. General objective is to prevalence of personality disorder in late adolescence with drug abuse. Specific objectives are to identify types of personality disorders in DSM IV and to identify most common personality disorder in late adolescence with drug abuse. This was a descriptive study. All participants were male. Interview based questioner was used for data collection and Used 120 participants in rehabilitation centers were interviewed. Approximately 79.2% clients were 19 years old, 16.7% were 20 years old and 4.2% were 21 years old in the sample.88.3% were unemployed and seeking work. 5% were full time students, 2.5% were part time employed, while full time employed and full time home makers were 1.7%. Approximately 83.3% were educated up to GCE(O/L), 7.5% were educated up to GCE(A/L), 5% were educated up grade 6- 10, 2.5% were in diploma level, while grade 1- 5 and graduate level were 0.8%. Among late adolescents who had personality disorder due to drug abuse, the majority were borderline affected personalities. Its valid percentage is 34.2%. Then valid percentage of dependent personality is 15%, Paranoid personality 14%, Avoidant personality 10%, Narcissistic personality 8%, and Schizotypal personality 6%. Further Obsessive compulsive personality 5%, antisocial personality 4%, Schizoid personality3% and histrionic personality 1%. These data show that there is a high prevalence of personality disorders in late adolescence with drug abuse.Item The Changing Composition: Are Young SLE Speakers Familiar with Youtube Slang?(Faculty of Graduate Studies, University of Kelaniya, Sri Lanka, 2016) Perera, N.Sri Lankan English (SLE) has been widely used by native SLE speakers for several decades. So far, SLE was believed to be influenced by the vernacular languages of the country, which consists of, but not limited to, Sinhala, Tamil and Malay. However, of late, the composition of the language has been changing and the vocabulary is one area where the change is seen distinctly. The researcher has focused on the use of slang by young SLE speakers for the current study. Slang terms usually make a trending entry into the vocabulary. In terms of SLE, the researcher has observed that there is an influence of slang used internationally on the slang terms used by the young SLE speakers, as SLE speakers are ‘connected’ to the world and come in contact with online slang terms. For the purpose of the study the domain of YouTube was selected, as it gives access to unscripted clips of speech. This quantitative study investigates if the young SLE speakers are familiar with some of these slang terms. The data for the study was collected from YouTube videos from the channel named HigaTV. It is the vlog channel (video log channel) of Ryan Higa who is the nineteenth most subscribed YouTuber. The slang terms selected from the videos were used in a questionnaire. The survey was administered online among 150 participants and 75 responses were used for the data analysis. The respondents expressed their familiarity with each word in the questionnaire, which was measured using a three point Lickert scale with the choices very familiar, familiar and not at all familiar. From a total of 19 words, eight were very familiar to more than 50% of the population while six others were marked ‘very familiar’ by more than 35% of the population. In a further analysis of the meanings of the words ‘duct tape’ and ‘legit’, more than 50% of the respondents stated that they knew the words. However, some meanings they associated with the words were not the same as the meanings in the videos. The majority of the respondents were from Colombo and suburbs. Hence it was concluded that, within the population, the young SLE speakers are familiar with some slang terms used by YouTubers and some of those terms are even used by the SLE speakers in their conversations. The research is however limited to identifying the speakers’ familiarity with the slang terms and does not provide an in depth analysis of the use of these terms. Future work on the topic could explore the familiarity of the slang terms among other age groups and also of speakers from different geographical locations.