Journal/Magazine Articles

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This collection contains original research articles, review articles and case reports published in local and international peer reviewed journals by the staff members of the Faculty of Medicine

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    Unusual pancytopenia secondary to haemophagocytosis syndrome in rickettsioses
    (Oxford University Press, 2009) Premaratna, R.; Williams, H.S.A.; Chandrasena, T.G.A.N.; Rajapakse, R.P.V.J.; Kularatne, S.A.M.; de Silva, H.J.
    We report two patients who presented with a long-lasting febrile illness associated with pancytopenia. Both of them had evidence of hypercellular marrow with haemophagocytosis. They were confirmed as having rickettsial infections by serology and had a rapid haematological recovery with anti-rickettsial antibiotics. We highlight the importance of considering rickettsial infections in patients with such clinical presentations, especially in areas where these infections are endemic or re-emerging. Empirical use of anti-rickettsial antibiotics in such situations could be beneficial, when facilities to diagnose rickettsial diseases are not readily available.