Journal/Magazine Articles
Permanent URI for this collectionhttp://repository.kln.ac.lk/handle/123456789/13
This collection contains original research articles, review articles and case reports published in local and international peer reviewed journals by the staff members of the Faculty of Medicine
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Item Intravenous N-acetylcysteine in dengue-associated acute liver failure(Springer International, 2010) Kumarasena, R.S.; Senanayake, S.M.; Sivaraman, K.; de Silva, A.P.; Dassanayake, A.S.; Premaratna, R.; Wijesiriwardena, B.; de Silva, H.J.No Abstract AvailableItem Adrenal hypersecretion(Sri Lanka Medical Association, 2007) Wijesiriwardena, B.; de Silva, D.C.Hypersecretion from the adrenal glands is associated with hypertension. Causes include Conn syndrome, Cushing syndrome and phaechromocytoma. This article discusses their clinical features, diagnosis and treatment as well as the management of incidentally identified adrenal tumours (incidentaloma).Item Adrenal insufficiency(Sri Lanka Medical Association, 2007) Wijesiriwardena, B.; de Silva, D.C.Adrenal insufficiency can be due to disease of the adrenal gland itself (primary adrenal deficiency) or of the hypothalamic or pituitary regulation of the adrenal gland (secondary adrenal insufficiency). This article discusses its causes, clinical features, diagnosis and treatment.Item The Adrenal glands and their functions(Sri Lanka Medical Association, 2007) de Silva, D.C.; Wijesiriwardena, B.The adrenal glands secrete hormones essential for metabolism, regulation of blood pressure, and sodium and glucose homeostasis. Hypo- or hypersecretion of these hormones is life threatening. Understanding the physiological functions of adrenal hormones is a prerequisite to the management of adrenal gland disease.Item Safety of subcutaneous adrenaline as prophylaxis against acute adverse reactions to anti-venom serum in snakebite(Sri Lanka Medical Association, 2002) Dassanayake, A.S.; Karunanayake, P.; Kasturiratne, K.T.A.A.; Fonseka, M.M.D.; Wijesiriwardena, B.; Gunatilake, S.B.; de Silva, H.J.OBJECTIVES: To study the safety of low dose subcutaneous adrenaline given as prophylaxis against acute adverse reactions to anti-venom serum(AVS) in patients bitten by snakes. METHODS: Patients admitted with snakebite envenoming who satisfied inclusion criteria were given 0.25 ml of 1:1000 adrenaline subcutaneously immediately before administration of AVS. They were observed for adverse effects, and pulse and blood pressure (BP) were monitored. RESULTS: 51 patients [35 males, mean age 34.8 years (SD 14)] were included in the study. Adverse reactions to AVS occurred in 15 (29.4%) patients. There was one death from suspected cerebral haemorrhage, and 3 (5.9%) patients developed small haematomas at the subcutaneous injection site. There were no significant changes in mean pulse or BP following administration of subcutaneous adrenaline. CONCLUSIONS: Low dose subcutaneous adrenaline did not cause significant changes in pulse rate or BP. Although the death was unlikely to be directly related to subcutaneous adrenaline, we suggest further studies on the safety of this prophylactic treatment before its routine use.Item Dyspepsia(Ceylon College of Physicians, 2001) Wijesiriwardena, B.; de Silva, H.J.Item Neuroleptic malignanat syndrome without fever: a report of three cases(BMJ Publishing Group, 2000) Peiris, D.T.S.; Kuruppuarachchi, K.A.L.A.; Weerasena, L.P.; Seneviratne, S.L.; Tilakaratne, Y.T.; de Silva, H.J.; Wijesiriwardena, B.No Abstract Available.Item Methyldopa use should be restricted(Sri Lanka Medical Association, 1999) de Silva, H.A.; Hewavisenthi, J.; Wijesiriwardena, B.; Fonseka, M.M.D.No Abstract Available