Conference Papers

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This collection contains abstracts of conference papers, presented at local and international conferences by the staff of the Faculty of Medicine

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Subject: search.filters.subject.Liver transplantation

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    Knowledge, attitudes, and beliefs about liver transplantation among caregivers of children with liver diseases; a single centre experience from Sri Lanka
    (Sri Lanka Medical Association, 2023) Gunaratne, A.L.S.N.; Gunarathna, P.G.P.D.; Gunawardana, A.D.J.N.; Hansamali, U.V.S.; Heenkenda, H.M.A.N.; Ekanayaka, J.; Fernando, C.M.P.
    INTRODUCTION: Paediatric Liver transplantation (PLT) is evolving in Sri Lanka. There is no data documented related to caregivers' knowledge of PLT. OBJECTIVES: To determine the knowledge, attitudes, and beliefs about liver transplantation (LT) among caregivers of children with liver diseases. METHODS: A descriptive cross-sectional study was conducted among the caregivers attending the paediatric liver clinic at Ragama. The calculated sample size was 186. Data were collected using an interviewer-administered questionnaire. Descriptive statistics with SPSS 27.0 were used for analysis. Ethical approval was obtained from the Faculty of Medicine, Ragama. Since there were no previous similar studies, as the tool, we used a newly designed, pre-tested questionnaire which included the basic facts about the knowledge of LT. RESULTS: Of 186 caregivers, the majority were mothers (n=107, 57%). A mixed religious background was noted with Buddhists, Catholics, Islam and Hindus being 80%, 11%, 7% and 2% respectively. Most were educated up to or above the GCE ordinary level (n=180, 97%). The majority (n=124, 68%) were from low-income families with a monthly income of less than 50,000 LKR. Almost half of the participants, 89 (47.8%) knew someone who had undergone an LT. Knowledge of having PLT within the country, living donation, diseased donation, blood group matching and life-long medications were accurate in 171 (91.9%), 170 (91%, 75 (40%), 172 (92%), 116 (62%) respectively. Regarding the beliefs and attitudes towards LT, 170 (91%) were willing to donate and 144 (77%) indicated to support LT. There were 32 (17%) who believed that liver diseases can be cured with alternative medicine and 103 (55%) believed being religious would result in better outcomes. CONCLUSION: Knowledge of LT among caregivers is promising with a positive attitude. Some of their beliefs seem to be non-scientific.
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    Liver transplantation - initial experience at Colombo North Liver Transplantation Service
    (Sri Lanka Medical Assosiation, 2012) Bogamuwa, M.M.M.P.; Siriwardana, R.C.; Niriella, M.A.; Dassanayake, A.S.; Wijesuriya, S.R.E.; Liyanage, C.A.H.; Gunetilleke, M.B.; de Silva, H.J.
    INTRODUCTION: Liver transplantation (LT) is the treatment of choice for end stage liver diseases. LT is still in its infancy in Sri Lanka. AIMS: To describe the initial experience of the Colombo North Liver Transplantation Service (CNLTS) METHODS: The study population included all patients referred for LT to CNLTS. All cases were evaluated for the indication and medical, social and psychological suitability for LT. Decision to list patients for LT was reached by a multidisciplinary team consisting of surgeons, physicians and anaesthetists. All data were collected prospectively. RESULTS: 52 patients were referred for LT over a period of 7 months. 48/52[92.3%) were males. The median age at referral was 52(range 13-66) years. The median Child-Turcotte-Pugh(CTP) score at referral was 9/15(range 5-13/15). Median Model for End Stage Liver Disease (MELD) score at referral was 17(range 9-26). 3/52(5.8%) had hepatocellular carcinoma and 9/52(17.3%) had a low MELD score (<14) but with life threatening complications of cirrhosis as indication. 4/9(44.4%) of those being upper gastrointestinal bleeds from varices. 28/52(53.8%) of the referrals had cryptogenic cirrhosis (CC), 18/52(34.6%) had alcoholic cirrhosis, 2/52(3.8%) each had metabolic, congenital and other causes for cirrhosis. 7/52(13.5%) transplants were performed [3 Live Donor LTs(LDLT) and 4 Deceased Donor LTs(DDLT)]. 5/7(71.4%)[2 - LDLT, 3 -DDLT] had a successful LT outcome. 11/45(24.4%) patients died while on the LT waiting list. CONCLUSIONS: High MELD CC was the commonest reason for referral for LT in our group. There was a high waiting list mortality highlighting the need for an efficient DDLT service.