Conference Papers

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This collection contains abstracts of conference papers, presented at local and international conferences by the staff of the Faculty of Medicine

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2008 - 200912010 - 20151

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Author: search.filters.author.Pathmeswaran, A.Subject: search.filters.subject.metabolic syndrome

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    Markers of metabolic syndrome among 14 year old adolescents in the Ragama Medical Officer of Health area
    (Sri lanka Medical Association, 2015) Jayasinghe, Y.C.; Kasturiratne, A.; Niriella, M.A.; Kottahachchi, D.C.; Rajindrajith, S.; Pathmeswaran, A.; de Silva, H.J.; de Silva, S.T.
    INTRODUCTION AND OBJECTIVES: Metabolic syndrome (MetS) is strongly associated with cardiovascular disease and diabetes. Local data on MetS do not cover the adolescent population. Our study describes clinical and biochemical markers of metabolic syndrome among adolescents in the Ragama Medical Officer of Health area. METHOD: Fourteen year old adolescents resident in the Ragama Medical Officer of Health area were invited to the study through the public health network. Socio-demographic and anthropometric data of adolescents who presented were collected by trained data collectors. Relevant bio-chemica! assays were conducted in the fasting state. Prevalence of identified markers of the MetS was determined. RESULTS: 508 adolescents participated [263 (51.8%) girls]. The median age at menarche among the girls was 12 years. 46 (18.8%) boys and 55 (20.9%) girls had a BM1 greater than age-sex equivalent of 23 kgrrr2 in adults. 39 (15.9%) boys and 95 (36.1%) girls had a waist circumference above the MetS cut-off for age and sex. 17 (6.9) boys and 16 (6.1%) girls had elevated triglycerides while none had decreased HDL. Two (0.8%) girls had fasting plasma glucose above lOOmg/dl. Eight (3.3%) boys and six (2.3%) girls had elevated blood pressure. One girl was positive for three of the five diagnostic criteria of MetS giving a prevalence of 2 per 1000. Only 190 (77.6%) boys and 159 (60.5%) girls were free of alt five markers of MetS. CONCLUSION: Our findings show that markers of MetS are prevalent in this urban adolescent population. These data provide a basis for planning interventions at community and school level.
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    Prevalence of metabolic syndrome in a Sri Lankan community
    (Sri Lanka Medical Association, 2008) Chackrewarthy, S.; Gunasekera, D.; de Silva, L.D.R.; Pathmeswaran, A.; Wijekoon, C.N.; Ranawaka, U.K.; Mizoue, T.; Kato, N.
    OBJECTIVE: To estimate the prevalence of metabolic syndrome (MetS) in a Sri Lankan community. Limited information is available about MetS in Sri Lankans. DESIGN, SETTING AND METHODS: A total of 2948 individuals (1345 males and 1603 females) who participated in the Ragama Health Study comprised the study population. Prevalence of MetS was estimated using three widely used criteria: International Diabetes Federation (IDF), WHO and National Cholesterol Education Programme - Adult Treatment Panel III (NCEP-ATP III). RESULTS: Age and sex adjusted prevalence rates of MetS were 38.9%, 38.9% and 41.6% as defined by IDF, WHO and NCEP-ATP III respectively. Prevalence increased with age (for age groups 35-44, 45-54 and 55- 65 years respectively; IDF - 27.9%, 40,1%, 42.9% ; WHO - 28.7%, 43.2%, 52.6%; NCEP ATP III - 34.6%, 46.7%, 50.6%; P<0.001 in all). MetS was commoner in women (IDF - 45.8% Vs. 23.0%, P<0.001; WHO - 37.3% Vs. 40.5%, P>0.05; NCEP-ATP III - 49.8% Vs. 33.1%, P<0.001). Prevalence of central obesity (using Asian cutoff values) was higher in women. (70.8% Vs. 35.5%, P<0.001). CONCLUSION: Prevalence of MetS is high in this community. Preventive measures towards reducing trie risks associated with MetS should be promoted.