Conference Papers

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This collection contains abstracts of conference papers, presented at local and international conferences by the staff of the Faculty of Medicine

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    The Association between adverse life events and abdominal pain-predominant functional gastrointestinal disorders.
    (Lippincott Williams & Wilkins, 2015) Devanarayana, N.M.; Rajindrajith, S.; Benninga, M.A.
    BACKGROUND: Abdominal pain-predominant functional gastrointestinal disorders (AP-FGIDs) are a common public health problem in children. The precise aetiology of AP-FGIDs is far from clear. Psychological stress and all forms of child abuse are known predisposing factors to develop AP-FGIDs. The main objective of this study is to study the association between adverse life events (ALEs) and development of AP-FGIDs. METHODS: A cross sectional, school based study was conducted in Gampaha district of Sri Lanka. All children aged 13-18 years were recruited from four randomly selected semi-urban schools in the district after obtaining consent from parents, school administration and children themselves. A translated and validated, self-administered questionnaire consisting of four parts was used for data collection. Part I was the Rome III questionnaire for functional gastrointestinal disorders, self-report form for children above 10 years. Part II was a questionnaire on exposure to adverse life events. Part III was the Sinhala (the native language) version of the PedsQL, Pediatric Quality of Life Inventory 4.0 (Generic Core Scales). Part IV was the Child Somatization Inventory. The questionnaire was administered under examination setting to ensure confidentiality and privacy. Research assistant were present during filling the questionnaire for provide assistance and verifications. AP-FGIDs were defined using the Rome III criteria. RESULTS: A total of 1792 children were included in the analysis (males 975 [54.4%], mean age 14.4 years, SD 1.3 years years). Out of them, 305 (17.0%) had AP-FGIDs. ALEs that showed a significant association with AP-FGIDs include, parental substance abuse (25.1% vs. 16.0% in controls, p = 0.015) and domestic violence (28.5% vs. 16.1%, p = 0.02). Children with AP-FGIDs exposed to ALEs have a higher somatization index compared to children not exposed to ALEs (16.9 vs. 13.4, p = 0.003), and a lower overall health-related quality of life (HRQoL) score (81.8 vs. 85.1, p = 0.02). The scores they obtained for psycho-social (86.4 vs. 92.4, p < 0.0001) and emotional (72.5 vs. 77.7, p = 0.03) domains of the HRQoL were also lower than that of children with no such experiences. CONCLUSIONS: Exposure to ALEs predispose children to develop AP-FGIDs. Experience of childhood ALEs deleteriously affects the HRQoL and somatization of children with AP-FGIDs.
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    Abnormal personality traits in children with aerophagia
    (Lippincott Williams & Wilkins, 2015) Devanarayana, N.M.; Jayawickrama, N.; Gulegoda, I.C.; Rajindrajith, S.
    OBJECTIVE: The main objective of this study is to study the personality types in children with aerophagia. METHODS: A cross sectional survey was conducted in 8 randomly selected schools in 4 randomly selected provinces Sri Lanka. From each school, all children aged 13-18 years were selected after obtaining written consent from parents, school administration and provincial education office. Assent was obtained from all children recruited. Date were collected using a self-administered questionnaire administered under examination setting to ensure confidentiality and privacy. Questionnaire contained previously translated and validated Rome III questionnaire for functional gastrointestinal diseases (self-administered form for children above 10 years) and childhood personality assessment questionnaire. Trained research assistants were present during filling the questionnaire to provide assistance and to verify doubts. Aerophagia was defined using the Rome III criteria. Severities of individual symptoms were recorded in 100 mm visual analogue scale. RESULTS: A total of 1069 questionnaires were distributed and all of them were returned and included in analysis [males 508 (47.5%), mean age 15.3 years, SD 1.8 years years]. One hundred and thirty six (12.7%) fulfilled Rome III criteria for aerophagia and 933 children without aerophagia were considered as controls. Nineteen (13.8%) children with aerophagia and 71 (7.6%) controls had personality scores above the international cut-off value (105) for abnormal personality (p = 0.01). Children with aerophagia had significantly higher scores for different personality traits than controls; including hostility and aggression (13.2 vs. 12.2 in controls, p = 0.006), negative self-esteem (11.0 vs. 9.9, p < 0.0001), negative self-adequacy (10.6 vs. 9.6, p = 0.001), emotional unresponsiveness (10.5 vs. 9.6, p < 0.0001), emotional instability (16.9 vs. 15.7, p < 0.001), negative world view (10.9 vs. 10.1, p = 0.02) and total personality score (92.1 vs. 87.7, p = 001). In children with aerophagia, scores obtained for severity of bloating correlated with scores obtained for hostility and aggression (r = 0.22, p = 0.02). CONCLUSIONS: Children with aerophagia has abnormal personality traits and this fact may at least partly responsible for development and perpetuation of symptoms in them.
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    Aerophagia in children is associated with emotional ill-treatment.
    (Lippincott Williams & Wilkins, 2015) Rajindrajith, S.; Silva, R. L.; Devanarayana, N.M.
    BACKGROUND: Aerophagia is a functional gastrointestinal disease characterized by air swallowing, abdominal distension, excessive flatus and belching. The aetiology of this disorder is not clear. Previous studies have suggested an association between aerophagia and psychological stress. We aimed to assess the association between emotional ill-treatment and aerophagia. METHODS: A cross sectional survey was conducted in 4 provinces of Sri Lanka. Children aged 13-18 years were selected from schools in these provinces. A validated, self-administered questionnaires were used for collect data on functional gastrointestinal disease including aerophagia and emotional ill-treatment. Aerophagia was defined using the Rome III criteria. RESULTS: A total of 1069 questionnaires were included in the final analysis (males 508 [47.5%], mean age 15.3 years, SD 1.8 years). One hundred and thirty six (136) children had aerophagia. Prevalence of aerophagia was significantly higher in children who experienced emotional ill-treatments (43 (23.2%) vs. 160 (17.1%), p < 0.0001). Emotional ill-treatments that were significantly associated with aerophagia include, teasing by others (54.1% vs. 45.0%, p < 0.0001), humiliation (38.2% vs. 20.3%, p < 0.0001), treating inferiorly by others (22.8% vs. 11.1%, p < 0.0001), threatening to abandon (8.8% vs. 2.6%, p < 0.0001), threatening destroy belongings (14.0 vs. 4.5%, p < 0.0001), and forcing to do unwanted deeds (9.6% vs. 3.9, p = 0.003). Parenting factors such as refusal of attending to emotional needs (8.8% vs. 3.0%, p < 0.001), refusal to look at (6.6% vs. 0.7%, p < 0.0001), refusal of hugging (10.5% vs. 5.6%, p = 0.03), and not appreciating achievements (5.9% vs. 2.1%, p < 0.0001) were significantly common among children with aerophagia. CONCLUSIONS: Aerophagia in children is associated with emotional ill-treatments. Attending to child's emotional needs likely reduce the prevalence of aerophagia and its consequences.