ARS - 2010

Permanent URI for this collectionhttp://repository.kln.ac.lk/handle/123456789/168

Browse

Now showing 1 - 2 of 2

Iodine concentration of household salt and its effect on serum TSH level of children aged 5- years
(Research Symposium 2010 - Faculty of Graduate Studies, University of Kelaniya, 2010) Abeysuriya, V.; Wickremasinghe, A.R.; Perera, K.P.J.; Kasturiratne, A.
Objective To describe the effects of household practices of salt usage on Iodine concentration in salt and the relationship between low Iodine concentration of salt and serum thyroxin level of children aged 5- years. Method A descriptive cross sectional study was carried out in two phases in 2randomly selected estates in the Ratnapura district from August to November, 2009. In phase one, using a pre-tested interviewer administered questionnaire, 1683 households were surveyed to identify the pattern of salt usage. Salt samples of these houses were tested for adequacy of iodine concentration (>30ppm of Iodine) using standard rapid iodine test kits. In phase two, blood samples of 51randomly selected children aged 5-years, from the same estates were taken after obtaining informed written consent from parents and serum TSH levels were assayed. Ethical clearance was obtained from the Ethics Committee of the Faculty of Medicine, University of Kelaniya. Results 36.4% of households purchased salt from the retail boutique closest to them. Purchase from shops in town, shops in the village, and estate cooperative shops was reported by 27.7%, 24.4% and 13.3%. Salt powder was used by 54.5% households while salt crystals were used by the rest. 82.7% did not wash salt before use 9.6% kept salt containers near the fire place. 38.8% households stored salt in plain glass bottles and 19.3% in dark coloured glass bottles. Usage of coconut shells and plastic bottles were 21.4% and 20.4%. Adequate iodine levels were present in 88.7% of household salt samples tested. Inadequate levels ofiodine was associated with keeping the container near fire place, use of glass containers to store salt and washing salt before use (p<0.01 for all variables). The place of purchase was not associated with the iodine level. The mean TSH levels of children whose household salt had an adequate iodine level (> 3ppm) was significantly lower (n=4171.861.11 IU/ml) from that of children whose household salt had an inadequate iodine level (< 30ppm) (n=1023.291.26 IU/ml). Conclusion Place of purchase has no effect on iodine concentration of household salt. Storing salt near the fire, use of glass containers to store salt and washing before use reduces its iodine concentration significantly. Household salt with an inadequate iodine concentration was associated with higher serum TSH levels in children 5-years of age.
Iodine concentrations of spring water and serum TSH levels in 5-year old children resident in the estates of the Ratnapura district
(Research Symposium 2010 - Faculty of Graduate Studies, University of Kelaniya, 2010) Abeysuriya, V.; Wickremasinghe, A.R.; Perera, K.P.J.; Kasturiratne, A.
Objective To determine the Iodine concentrations in drinking water sources of estate population of the Ratnapura district and to determine the association between iodine levels of drinking water and Thyroid Stimulating Hormone (TSH) levels in children aged 5-years. Method A descriptive cross sectional study was carried out in three phases in 2randomly selected estates in the Ratnapura district from September to November, 2009.In phase 1, 1683 households were surveyed to identify common drinking water sources in the selected estates. In phase 2, blood samples from 51randomly selected children aged of 5-years from same estates were taken to assay TSH levels after obtaining informed written consent from parents. In phase 3, water samples from 23 identified sources (wells, rivers and springs) were obtained and were and analysed for iodine (I) levels by the catalytic reduction method. Based on elevation from mean sea level, water sources were grouped, and mean TSH levels and water Iodine concentrations were correlated. Ethical clearance was obtained from the Ethics Committee of the Faculty of Medicine, University of Kelaniya. Result The main source of drinking water was water springs (83.7%), followed by pipe-borne water (14.6%), rivers (1.5%) and wells (0.2%). Spring water at low altitudes had significantly higher Iodine concentrations than those located at higher altitudes (p=0.002). The mean spring water Iodine concentrations according to altitude were as follows36.005.66 g/dl at 100-200m (n=2), 16.256.52g/dl at 201-300m (n=8), 7.754.11g/dl at 301-400m (n=4) and 3.831.60g/dl above 401m (n=6). The mean iodine levels of spring water (12.810.63g/dl) were significantly lower compared to other water sources (130.0112.12g/dl) (p=0.0001). The mean TSH levels of children according to altitude were as follows1.781.15IU/ml at 100-200m, 2.210.64IU/ml at 201-300m, 2.170.46IU/ml at 301-400m and 2.040.17IU/ml >401m. There was no association between TSH concentrations of children and iodine levels of spring water at different altitudes (p=0.69). Conclusions The majority in the estates consume spring water. The iodine concentration of spring water was significantly lower as compared to other water sources. Iodine levels of spring water were significantly higher at lower altitudes than at higher altitudes. There was no association between serum TSH levels in children aged 5-years and iodine levels of spring water at different altitudes.