25th Anniversary International Scientific Conference-2016

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Plenaries, Symposia and free papers presented at the 25th Anniversary International Scientific Conference, held on 6-8th April 2016, Faculty of Medicine, University of Kelaniya to celebrate the Silver Jubilee Anniversary of Faculty of Medicine

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    Impact of hypertension on mortality: Findings from the Ragama Health Study
    (Faculty of Medicine, University of Kelaniya, Sri Lanka, 2016) Kasturiratne, A.
    The relationship of hypertension on mortality is well known. In Sri Lanka this relationship has not been quantified in a comprehensive analysis. The objective of the presentation will be to describe the relationship of incident and prevalent hypertension on the 7-year cardio-vascular and all-cause mortality in the Ragama Health Study (RHS) cohort. RHS is a prospective cohort study that recruited nearly 3000 adults between 35-64 years of age resident in the Ragama Medical Officer of Health area in 2007. The participants were sampled using an age-stratified random sampling technique to represent the three 10-year age groups. Baseline assessment of the cohort included socio-demographic, lifestyle, anthropometric and clinical assessments. The cohort was followed up in 2010 and 2014 to determine incidence of important clinical outcomes. 7-year mortality of the cohort was determined through comprehensive community surveys conducted in 2012 and 2014/15. The RHS cohort comprises 2986 individuals who participated in the baseline survey. By the end of 2014, 107 participants had died. The all-cause mortality was significantly associated with a higher systolic hypertension at baseline after controlling for age and sex. One Hg mm increase in systolic blood pressure was associated with 1.02 times increase in all-cause mortality. This presentation will discuss the anthropometric, lifestyle, bio-chemical and clinical characteristics associated with the prevalence and the incidence of hypertension, and cardio-vascular and all-cause mortality over the seven year follow up period.
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