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Browsing by Author "Gunawardena, N.K."

Browsing by Author "Gunawardena, N.K."

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  • Achieving millennium development goal 4 in 2015: are we really on track? 
    Mettananda, S.; Rajindrajith, S.; Warnakulasuriya, T.; Fernando, M.; Devanarayana, N.M.; Gunawardena, N.K. (Sri Lanka College of Paediatricians, 2011)
    INTRODUCTION: Millennium development goal (MDG) 4 aims to reduce under 5 mortality by two thirds from 1990 (22.2 per 1000 live births) to 2015 (7.4 per 1000 live births). In achieving this, proper and accurate description ...
  • Adjusting for spatial variation when assessing individual-level risk: A case-study in the epidemiology of snake-bite in Sri Lanka 
    Ediriweera, D.S.; Kasturiratne, A.; Pathmeswaran, A.; Gunawardena, N.K.; Jayamanne, S.F.; Murray, K.; Iwamura, T.; Lalloo, D.G.; de Silva, H.J.; Diggle, P.J. (Public Library of Science, 2019)
    BACKGROUND:Health outcomes and causality are usually assessed with individual level sociodemographic variables. Studies that consider only individual-level variables can suffer from residual confounding. This can result ...
  • Allergic sensitization in children 
    Amarasekera, N.D.D.M.; Gunawardena, N.K.; de Silva, N.R.; Weerasinghe, A. (The Sri Lanka College of Paediatricians, 2008)
    BACKGROUND :Allergic sensitization is considered a significant risk factor for the development of atopic diseases. Appropriate allergen avoidance measures can be taken only when the pattern of sensitization to allergens ...
  • Association between asthma and rhinitis 
    Amarasekera, N.D.D.M.; Gunawardena, N.K.; de Silva, N.R.; Weerasinghe, G.A.K. (Sri Lanka Medical Association, 2010)
    INTRODUCTION AND OBJECTIVES: It has been suggested that'both asthma and allergic rhinitis are manifestations of a single disease and they are related epidemiologically and pathophysiologically. The objective was to assess ...
  • Association between serum total IgE, allergic diseases and geohelminth infections in Sri Lankan children 
    Amarasekera, N.D.D.M.; Gunawardena, N.K.; de Silva, N.R.; Douglass, J.; O’Hehir, R.E.; Weerasinghe, A. (BioMed Central, 2007)
    BACKGROUND: Elevated levels of total IgE (tIgE) in serum are characteristic of allergic diseases. Levels of tIgE are influenced by genetic predisposition, age, sex and helminth infections. However, the association between ...
  • Bihar's pioneering school-based deworming programme: lessons learned in deworming over 17 million Indian school-age children in one sustainable campaign. 
    Drake, L.J.; Singh, S.; Mishra, C.K.; Sinha, A.; Kumar, S.; Bhushan, R.; Hollingsworth, T.D.; Appleby, L.J.; Kumar, R.; Sharma, K.; Kumar, Y.; Raman, S.; Chakrabarty, S.; Kihara, J.H.; Gunawardena, N.K.; Hollister, G.; Kumar, V.; Ankur, A.; Prasad, B.; Ramachandran, S.; Fishbane, A.; Makkar, P. (San Francisco, CA : Public Library of Science, 2015)
  • A Case of imported malaria: the first report of Plasmodium malariae infection in Sri Lanka after 37 years 
    Hapuarachchi, H.A.C.; Gunawardena, N.K.; Senevirathne, M.P.; Abeyewickreme, W.; de Silva, N.R. (Sri Lanka Medical Association, 2008)
    We report a case of Plasmodium falciparum and P. malariae mixed infection in a patient who had been living in Malawi. This is the first case of P. malariae reported in Sri Lanka in 4 decades. The presence of both parasites ...
  • Chemotactic response of Brugia pahangi infective larvae to jird serum in vitro 
    Gunawardena, N.K.; Fujimaki, Y.; Aoki, Y. (Springer International, 2003)
    The Brugia pahangi infective larval response to jird serum was studied using an agar plate assay. Larvae placed onto the agar remained at the same place for 60 min. Once the larvae were stimulated by serum, more than 95% ...
  • Cluster randomized trial of the impact of school based deworming and weekly iron supplementation on haemoglobin level of plantation primary school children 
    Ebenezer, R.; Gunawardena, N.K.; Kumarendran, B.; Pathmeswaran, A.; de Silva, N.R. (College of the Community Physicians of Sri Lanka, 2013)
    BACKGROUND: School-based deworming and iron supplementation are being promoted as effective interventions to deal with the high prevalence of anaemia among school children. OBJECTIVE: The objective of this study was to ...
  • Community incidence of snakebite and envenoming in Sri Lanka; results of a national survey 
    Pathmeswaran, A.; Kasturiratne, A.; Gunawardena, N.K.; Wijayawickrama, B.A.; Jayamanne, S.F.; Ediriweera, D.S.; Isbister, G.; Dawson, A.; Lalloo, D.G.; de Silva, H.J. (Sri Lanka Medical Association, 2014)
    INTRODUCTION AND OBJECTIVES: We undertook the first ever country-wide community-based survey to determine the incidence of snakebite in Sri Lanka. METHODS: Data were collected through household interviews by trained data ...
  • Community incidence of snakebite in the Amiradhapura district 
    Kasturiratne, A.; Gunawardena, N.K.; Wijayawickrama, B.A.; Jayamanne, S.F.; Pathmeswaran, A.; Isbister, G.; Dawson, A.; de Silva, H.J. (Sri Lanka Medical Association, 2013)
    INTRODUCTION AND OBJECTIVES: The community incidence of snakebite in Sri Lanka is unknown. To investigate incidence of snakebite, we undertook a community study in the Anuradhapura district as part of an ongoing countrywide ...
  • Comparison of five DNA extraction methods from human blood for the detection of Wuchereria bancrofti by polymerase chain reaction assays 
    Wijegunawardana, N.D.A.D.; Gunawardene, Y.I.N.S.; Manamperi, A.; Hapuarachchi, H.A.C.; Gunawardena, N.K.; Abeysundara, S.; Abeyewickreme, W. (Sri Lanka Association for the Advancement of Science, 2008)
    Introduction: Lymphatic filariasis (Lf) is the second most common vector-borne disease globally. Approximately 90% of global burden of Lf is caused by Wuchereria bancrofti. W. bancrofti is routinely diagnosed by morphological ...
  • Comparison of laboratory techniques for diagnosis of hookworm infections 
    Manamperi, N.H.; Anjalee, K.G.C.; Gunawardena, N.K.; Sudusinghe, H.; Nilaweera, T.H.W.T.; de Silva, N.R. (Sri Lanka College of Microbiologists, 2011)
    INTRODUCTION: Hookworm infection may be diagnosed by detection of eggs or culturing of larvae from stools. OBJECTIVE: To compare the efficacy of modified Kato-Katz (K-K) technique, saline smears, Harada-Mori (H-M) and ...
  • Correction: Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka. 
    Shinsugi, C.; Gunasekara, D.; Gunawardena, N.K.; Subasinghe, W.; Miyoshi, M.; Kaneko, S.; Takimoto, H. (Public Library of Science, 2020)
    [This corrects the article DOI: 10.1371/journal.pone.0224222.]. Erratum for Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka. PLoS One.2019;14(10):e0224222.
  • Development of a Snakebite risk map for Sri Lanka 
    Ediriweera, D.S.; Kasturiratne, A.; Pathmeswaran, A.; Gunawardena, N.K.; Wijayawickrama, B.A.; Jayamanne, S.F.; Isbister, G.K.; Dawson, A.; Giorgi, E.; Diggle, P.J.; Lalloo, D.G.; de Silva, H.J. (Sri Lanka Medical Association, 2016)
    INTRODUCTION: Snakebite is a public health problem in Sri Lanka and about 37,000 patients are treated in government hospitals annually. At present, health care resources which are required to manage snakebite are distributed ...
  • Differential effects of diethylcarbamazine, tetracycline and the combination on Brugia pahangi adult females in vitro 
    Gunawardena, N.K.; Fujimaki, Y.; Aoki, Y.; Mishima, N.; Ezaki, T.; Uni, S.; Kimura, E. (Elsevier, 2005)
    Anti-filarial effects of diethylcarbamazine (DEC), tetracycline (TC) and the combination on Brugia pahangi adult females were studied in 7-day cell-free culture, in terms of microfilaria release, parasite motility, MTT ...
  • The Diversity of Human Dirofilariasis in Western Sri Lanka 
    Chandrasena, T.G.A.N.; Premaratna, R.; Mallawaarachchi, C.H.; Gunawardena, N.K.; Gunathilaka, P.A.D.H.N.; Abeyewickrama, W.Y.; de Silva, N.R. (Hindawi Pub. Co, 2019)
    BACKGROUND:Human dirofilariasis is an emerging zoonosis in many countries. Dirofilariasis caused by Dirofilaria repens may present with diverse clinical manifestations in humans due to aberrant localization of worm lesions ...
  • Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka 
    Shinsugi, C.; Gunasekara, D.; Gunawardena, N.K.; Subasinghe, W.; Miyoshi, M.; Kaneko, S.; Takimoto, H. (Public Library of Science, 2019)
    Child malnutrition and maternal obesity are serious public health issues in Sri Lanka. This study explores the associations between socioeconomic status and the double burden of malnutrition among school-aged children and ...
  • Effect of genotyping on the severity of rotavirus Gastroenteritis 
    Chandrasena, T.G.A.N.; Rajindrajith, S.; Gunawardena, N.K.; Silva, G.M.K.S.; Pathmeswaran, A.; Kazuhiko, M.; Kamruddin, A. (Sri Lanka College of Paediatricians, 2011)
    INTRODUCTION: Rotavirus is the commonest cause of paediatric gastroenteritis. There remains a controversy regarding disease severity being related to rotavirus genotype G9. OBJECTIVE: Study the genotype related severity ...
  • The Effect of intestinal nematode infections on atopic diseases in children 
    Amarasekera, N.D.D.M.; Gunawardena, N.K.; de Silva, N.R.; Douglas, J.; O'Hehir, R.; Weerasinghe, A. (Allergy and Immunology Society of Sri Lanka, 2009)
    BACKGROUND : The effect of helminth infections on atopic diseases and allergic sensitization is controversial. Little is known about the effect of infection on atopic diseases in children living in areas where both intestinal ...

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