Browsing by Author "Weerasooriya, W.M.B."

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Analysis of the metal content in Ayurvedic medicated oil; Vāthavidurangādī thaila
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Jayasinghe, R.N.S.; Weerasooriya, W.M.B.; Rajapakshe, C.S.K.
The Ayurvedic medicines of herbo-mineral origin are widely used in Sri Lanka. The metal contamination in such products is frequently reported in recent years. As accumulation of excessive amount of metals in the human body leads to various health hazards, the precise determination of such contaminants is required for safety assurance before usage. The Ayurvedic medicated oil, Vāthavidurangadī Thaila, is a popular medication prescribed by Ayurvedic physicians to treat several diseases and disorders. Therefore, this study was conducted to determine the concentration of selected metals in commercially available samples of Vāthavidurangadī Thaila using Atomic Absorption Spectrometry (AAS). The ten samples of Vāthavidurangadī Thaila collected from Colombo, Kandy, Kalutara, Galle and Gampaha districts were analyzed, for the content of Aluminum (Al), Copper (Cu), Cadmium (Cd), Chromium (Cr) and Lead (Pb) after acid digestion of samples with conc. HNO3 ,H2O2 and 70% HClO4. According to the results, Cu was found in all samples, Cr was detected in six samples but Pb was detected only in four samples. Al, Cu, Cd, Cr and Pb contents in oil samples were found in the range of 0.29-9.54 ppm, 2.34-10.80 ppm, 0.04-0.25 ppm, 3.02-4.39 ppm and 0.98-2.81 ppm respectively. The mean concentration values of Al, Cu, Cd, Cr and Pb were 4.7088 ppm, 4.7844 ppm, 0.0576 ppm, 1.5912 ppm and 0.8568 ppm respectively. The trend of abundance of metals in oil samples of Vāthavidurangadī Thaila followed the sequence of Cu >Al > Cr > Pb >Cd. According to the results, Al and Cr contents in some of the oil samples were higher than the maximum allowable limit recommended by WHO in drinking water. Chromium and Aluminum are not permissible for herbal medicines according to the WHO standards but Cd, Pb, Cu contents in all oil samples were lower than the maximum allowable limit recommended by WHO in herbal medicines.
Chemical and microbiological analysis of Arishta and Asava with reference to the herbal pharmaceutical standardization
(2013) Weerasooriya, W.M.B.
A comparative analysis of Hinguashtaka Churna in marketed samples
(Sri Lanka Association for the Advancement of Science, 2013) Samarathunga, D.K.; Gunaratna, T.A.N.R.; Weerasooriya, W.M.B.; Liyanage, J.A.
Determination of Ash content in Varatika and Abhraka used in Ayurveda Rasa pharmaceuticals
(Sri Lanka Association for the Advancement of Science, 2011) Gunaratna, T.A.N.R.; Maduwanthi, J.A.H.; Weerasooriya, W.M.B.; Liyanage, J.A.
Varatika is the shell of Cyprea moneta (shell of cowry) and chemically it is identified as a carbonate of calcium (CaCO3). This is used in Rasa Shatra as a key ingredient. Among Abhraka varieties Krishna vajra abhraka (Biotite Mica) is the finest variety used for therapeutic purposes. Mineral compounds that are prepared through Shodhana (purification), Bhavana (trituration) and Marana (incineration) are considered pharmaceutically as the most suitable forms as they are superior, non-toxic and highly potent for therapeutic point of view. Owing to the superiority of mineral drugs in the place of herbal drugs it has been described that the supremacy might be due to their fast action in smaller dose with good palatability. Hence determination of the total ash content and the acid soluble ash content of Varatika and Abhraka bhashma are important, as it could be helpful to understand the effectiveness of those Ayurveda medicines in the human body. Purification of Varatika and Krishna vajra abhraka (six samples each) and preparation of Dhanyabhraka and Dhanyabhraka chakrika were carried out using traditional methods described in authentic Ayurveda texts. Samples were ashed using Muffel furnace and total ash content and acid soluble ash content were determined. Ash content of unpurified and purified Varatika was 55.64% and 57%, respectively. When compared with the traditionally incinerated sample it is lower (8.50%) than the sample incinerated in a Muffle furnace (14%). These results revealed the importance of improving traditional methods using modern techniques for the manufacture of quality Ayurvedic medicines and this result could be useful to interpret the therapeutic effect of Varatika Bhashma used in hyper acidity. The ash content of unpurified Abhraka was 0.94g (±0.00) in 1g of sample and it was 0.95g (±0.01) in 1g of purified sample. Acid soluble ash content has increased during the purification from 5% to 7.8%. Total ash content and acid soluble ash content of Dhanyabhraka was 0.92g (±0.01) and 10% respectively, and 0.66g (±0.01) ash amount was determined in Abhraka chakrika. Acid soluble ash content in Abhraka chakrika was 5.8%. These results highlight the significance of purification process in Ayurveda pharmaceutical preparation.
Determination of metal content in Rasna Sapthaka Kwatha
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Abeysingha, W.A.M.U.S.; Nilmini, R.R.P.S.; Rajapakse, C.S.K.; Weerasooriya, W.M.B.
Rasna sapthaka kwatha is a widely used Ayurvedic decoction. Medicinal plants that are the ingredients of this decoction are collected from different habitats of the country. The decoction can be contaminated with metals during the growing, collecting, and storing of the raw material and also during the processing of this product. Hence, the evaluation of metal concentration in pharmaceutically available decoction is of utmost significance. Therefore, the main objective of this research was to determine the concentration of Al, Cr, Cd, Cu, and Pb in decoction samples of Rasna sapthaka kwatha collected from different areas of Sri Lanka. Ten samples of decoction were randomly collected from Anuradhapura, Kurunegala, Kandy, Polonnaruwa, Thambuththegama, Galadiulwewa and Gampaha. Atomic Absorption Spectrometry was used to detect the metal concentration. Wet digestion was carried out prior to the analysis. The mean concentration value of Al, Cd, Cr and Cu were 1.010ppm, 0.232 ppm, 0.387 ppm and 0.155 ppm respectively. Pb was below the detected level of the instrument. Al, Cd, Cr and Cu contents in decoction samples were found in the range of 0.39-2.208 ppm, 0.18-0.348 ppm, 0.33-0.462 ppm, and 0.042-0.408 ppm respectively. Results revealed that the mean values of metal concentration of tested samples were below the recorded WHO permissible level of metals in herbal medicine.
Determination of the concentration of Mercury, Lead and Arsenic in selected ayurvedic medicine
(Sri Lanka Association for the Advancement of Science, 2010) Maduwanthi, J.A.H.; Weerasooriya, W.M.B.; Liyanage, J.A.
Determination of the concentrations of copper and iron in selected Ayurvedic preparations
(Sri Lanka Association for the Advancement of Science, 2009) Maduwanthi, J.A.H.; Weerasooriya, W.M.B.; Liyanage, J.A.
Determination of toxic heavy metals in selected Arishta used in Sri Lanka
(Gampaha Wickramarachchi Ayurveda Institute, 2009) Weerasooriya, W.M.B.; Liyanage, J.A.; Jayaratne, D.L.
The eastern perspective of causes of natural disasters w.s.r. to caraka samhita and selected Buddhist doctrines: review
(Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, 2014) Wewalwala, S.L.; Weerasooriya, W.M.B.
Evaluation of ion concentration in selected aurvedic preparations used for iron deficiency anemia
(Sri Lanka Association for the Advancement of Science, 2012) Gunaratna, T.A.N.R.; Maduwanthi, J.A.H.; Weerasooriya, W.M.B.; Liyanage, J.A.
Evaluation of uniformity of weight of selected Ayurveda medicinal pills in the market
(Sri Lanka Association for the Advancement of Science, 2013) Sandamali, N.; Weerasooriya, W.M.B.; Liyanage, J.A.
Identification of alcohols in selected arishta and asava used in ayurvedic medicine
(Sri Lanka Association for the Advancement of Science, 2006) Weerasooriya, W.M.B.; Liyanage, J.A.
Microbiological quality of Aravindasava used in Ayurveda
(Sri Lanka Association for the Advancement of Science, 2009) Weerasooriya, W.M.B.; Liyanage, J.A.; Jayaratne, D.L.
Nutritional status of pre-school children in the Kekirawa divisional secretariat area of the Anuradhapura district of Sri Lanka
(Sri Lanka Association for the Advancement of Science, 2013) Perera, K.P.D.C.; Weerasooriya, W.M.B.; Liyanage, J.A.
Preliminary study on total sugar concentrations and energy values of selected herbal pharmaceuticals
(Sri Lanka Association for the Advancement of Science, 2005) Weerasooriya, W.M.B.; Liyanage, J.A.; Chandimal, K.M.
A review of wound healing used by Bhathanwaththe tradition
(Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, 2014) Samarathunga, L.M.D.D.K.; Weerasooriya, W.M.B.; Liyanage, J.A.
Signs of Buddhism illustrated in sadvåtaya in Ayurveda
(Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Sri Lanka, 2016) Weerapperuma, W.D.D.; Weerasooriya, W.M.B.
Ayurveda is the discipline that describes the cause, symptoms and medicine for mental, physical and spiritual well-being which is known as healthy life. It evolved in India since 10th century B.C. Buddhism is stirring the life towards the well-being of physical, mental and spiritual status and to attain the nibbāna to overcome the rebirth to prevent from all dukkhas. The origin of Buddhism was in 6th century B.C. in India. Though Ayurveda evolved earlier than Buddhism, contents of Ayurveda were documented in 4th century B.C. When the documents were reviewed, it was observed that the factors described in Ayurveda show similarities with those of Buddhism. With this background, a review was carried out and factors were compared to identify the signs of Buddhism in sadvåtaya. The set of doctrine described in sadvåtaya has to be practiced for a healthy life. So, one who observes these principles simultaneously fulfill both the objectives which maintain positive health and the control of sense faculties. These illustrated factors highlight the signs of trividha puëya kriyä which are helpful to improve çéla, samädhi and prajïä in a person according to Buddhism. Further to this is the comparison of doctrine of sadvåtaya. The factors described in brahmacarya, païca çéla, dasa akusal, satara brahma viharaëa and dhammapadaya demonstrate the interlace of Buddhism with Ayurveda. When exploring sadvåtaya and contents of mahä maìgala, paräbhava, mahä käçyapa bojjanga, girimänanda, vasala, karaëéya metta, mettänisaàsa suttas together with comparable doctrine to improve physical, mental and spiritual well being in human could be identified. The review leads to identify the signs of Buddhism in sadvåtaya which has been described in Ayurveda.