Browsing by Author "Salvin, K."

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    Endophthalmitis caused by Kocuria kristinae: A Case Report (Case Reports)
    (Sri Lankan Society for Microbiology, 2020) Alles, M.; Wariyapola, D.; Salvin, K.; Jayatilleke, K.
    ABSTRACT: Kocuria kristinae is part of the microbiota of humans but can also act as an opportunistic pathogen causing invasive infection. Here we report a case of endophthalmitis in a previously healthy adult male presumably resulting from iatrogenic infection due to intra-vitreal administration of drugs for the management of macular oedema. Following trans pars plana vitrectomy, an aseptically obtained specimen of vitreous humor was processed for bacterial culture. A pure growth of K. kristinae was isolated which was identified via VITEK 2. The patient was treated with intra-vitreal vancomycin with subsequent improvement of his condition. KEYWORDS: Kocuria kristinae, Endophthalmitis, Vancomycin
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    Headache: an important symptom possibly linked to white matter lesions in thalassaemia.
    (Wiley-Blackwell, 2019) Premawardhena, A.; Ranawaka, U.; Pilapitiya, T.; Weerasinghe, G.; Hapangama, A.; Hettiarachchi, S.; Salvin, K.; Silva, I.; Hameed, N.; Weatherall, M.; Olivieri, N.; Weatherall, D.
    Neurological manifestations are reported only occasionally in patients with thalassaemia and are given much less prominence than the complications related to anaemia and iron overload. White matter changes (WMCs) on magnetic resonance imaging (MRI) in patients with thalassaemia were first reported two decades ago but the significance of these lesions remains unclear. We studied the neurological and cognitive manifestations in 82 older patients with thalssaemia [25 Thalassaemia major (TM), 24 thalassaemia intermedia (TI) and 33 haemaglobin E β thalassaemia (EBT)] and 80 controls, and found that headaches were more common in thalassaemia patients (50/82, 61%) than in controls (18/80, 22·5%: P < 0·001). WMCs on MRI were found in 20/82 (24·3%) patients and 2/29 (6·9%) controls had (P = 0·078). WMC were more common among those with headaches (17/50: 34%) than in those without headache (3/32; 9·3%) (P = 0·023). WMCs were not associated with reduction of cognition. Nevertheless, cognition was lower in the TI and EBT groups compared with those with TM (P = 0·002). The association of headache with WMC in thalassaemia has not been reported before and warrants further study.