Browsing by Author "Pinto, M. D. P."

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    Dietary goitrogens and prevalence of goitre in Sri Lanka
    (The College of Surgeons of Sri Lanka, 2011) Pinto, M. D. P.; Fernando, R.; Pathmeswaran, A.; Premathilake, M.; Fernando, T.; Edirisinghe, D.; Bandara, D.; Athulugama, N.; Abeysinghe, S.
    OBJECTIVE: To assess the relationship between dietary goitrogens and the prevalence of goiter. METHODS:A descriptive cross-sectional study on the prevalence of goitre was conducted involving all areas of the country, except North and Batticaloa district from December 2006 to June 2007. A pre-tested interviewer administered questionnaire was used on all participants as a screening tool. Consumption of 6 possible dietary goitrogens was assessed. Sufficient frequency of consumption was taken as consumption >3 times a week. Pearson's chi-square test was used to analyze the significance of dietary goitrogens to the prevalence of goiter. RESULTS: 5200 participants were assessed (n=5200) island wide and 426 were detected with goitre. Mean age for occurrence of goitre was 36.3(+_17.3) years. Frequency of consumption of these food items was low, none being higher than 10% among the 5200 participants. Consumption of each goitrogen was as follows; Cabbage "[2.9%], Lima beans [9.9%], Kurakkan (Millet) [4%], Turnip [2.9%], Manioc(Cassava) [2.2%] and Peanuts [5.5%]. All six dietary goitrogens showed no significant association with the occurrence of goitre (p<0 05).CONCLUSION:Dietary goitrogens do not appear to have an association with prevalence of goitre in this cohort. As this cohort is a representative sample, dietary goitrogens are unlikely to be associated with prevalence of goitre in Sri Lanka.
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    Our experience with breast carcinoma in Sri Lankan women- a single unit experience.
    (The College of Surgeons of Sri Lanka, 2011) Pinto, M. D. P.; Pathiraja, P. D. M.; Ariyarathne, M. H. J.
    INTRODUCTION: Breast cancer is the most frequently diagnosed life-threatening cancer in women and the leading cause of cancer death among women worldwide. There is no national breast cancer screening programme yet in Sri Lanka. METHODOLOGY: A retrospective analysis of breast cancer registry from 1999 to 2010 at the University Surgical Unit NCTH, was carried out. Presentation, tumour site, practise of self-breast examination (SBE), histology and risk factors were assessed. RESULTS: Study sample consisted of 110 women (mean age =52.6 years). 40.9% presented with accidental finding of a breast lump, 20% with breast pain, 6% with nipple discharge and 74.5% had never practiced SBE. Those who did not practice SBE (77.2 % ) had either T3 or T4 disease. Majority of tumours appeared in the upper outer quadrant -59.1% (upper medial 19.1 % lower outer 16.4%. ) with tumour size varying from 2-5 cm in 54.5% ( 5-10 cm - 30.1% and < 2 cm - 10.1%). The infiltrating duct carcinoma (79.1%) invasive lobular carcinoma (7.3%) and duct carcinoma in situ (5.5%) are the commonest histological types. Fine needle aspiration (FNAC) revealed duct carcinoma in 83.1% women. They showed 16.4% nulliparous and 20% were taking oral contraceptive pills for more than 5 years. CONCLUSION: The study demonstrates that most common histological type was infiltrating duct carcinoma and FNAC has a satisfactory correlation with final pathological diagnosis. The women who did not practise SBE had advanced breast carcinoma. public awareness and improved screening will lead to early diagnosis.