Browsing by Author "Mendis, N."
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Item Abdominal pain-predominant functional gastrointestinal diseases in children and adolescents: prevalence, symptomatology, and association with emotional stress(Lippincott Williams and Wilkins, 2011) Devanarayana, N.M.; Mettananda, S.; Liyanarachchi, C.; Nanayakkara, N.; Mendis, N.; Perera, N.; Rajindrajith, S.BACKGROUND AND OBJECTIVE: Functional gastrointestinal disorders (FGD) are common among children, but little is known regarding their prevalence in developing countries. We assessed the prevalence of abdominal pain-predominant FGD, in addition to the predisposing factors and symptomatology, in Sri Lankan children. PATIENTS AND METHODS: A cross-sectional survey was conducted among a randomly selected group of 10- to 16-year-olds in 8 randomly selected schools in 4 provinces in Sri Lanka. A validated, self-administered questionnaire was completed by children independently in an examination setting. FGD were diagnosed using Rome III criteria. RESULTS: A total of 2180 questionnaires were distributed and 2163 (99.2%) were included in the analysis (1189 [55%] boys, mean age 13.4 years, standard deviation 1.8 years). Of them, 270 (12.5%) had at least 1 abdominal pain-predominant FGD. Irritable bowel syndrome (IBS) was seen in 107 (4.9%), functional dyspepsia in 54 (2.5%), functional abdominal pain in 96 (4.4%), and abdominal migraine (AM) in 21 (1.0%) (2 had AM and functional dyspepsia, 6 had AM and IBS). Extra intestinal symptoms were more common among affected children (P < 0.05). Abdominal pain-predominant FGD were higher in girls and those exposed to stressful events (P < 0.05). Prevalence negatively correlated with age (r = -0.05, P = 0.02). CONCLUSIONS: Abdominal pain-predominant FGD affects 12.5% of children ages 10 to 16 years and constitutes a significant health problem in Sri Lanka. IBS is the most common FGD subtype present. Abdominal pain-predominant FGD are higher in girls and those exposed to emotional stress. Prevalence of FGD decreased with age. Extra intestinal symptoms are more frequent in affected children.Item Responsibility of media for the change of traditional food and eating habits(Department of English, University of Kelaniya, 2015) Dhammarathana Thero, B.; Mendis, N.; de Saram, H.The research focuses on Sri Lankan food and eating habits. Today the food have been changed due to various reasons and media is one effective factor for this change. Today television and magazines are filled with plenty of advertisements and most of them are concerned with food. They point out the positive side of that product and how that product is helpful to the consumer. They highlight the simple, quick and easiness of that product to use. Today media, that is mainly television and magazines or newspapers have given major place to advertisements and among them the advertisements on instant food compel the people to buy it. It is proposed to undertake the following approach as methodology in order to meet the research objectives. This research will consist of two primary stages. First stage consists of content analysis of primary and secondary sources and the second stage is a qualitative research by means of interviews. Information were gathered from the students, lecturers and few families in countryside and city. Through the information the conclusion was that media is highly effective for the change of traditional food and eating habits mainly in the cities than the villages.Item Schizophrenia treatment in the developing world: an interregional and multinational cost-effectiveness analysis(World Health Organization, 2008) Chisholm, D.; Gureje, O.; Saldivia, S.; Villalon Calderon, M.; Wickremasinghe, R.; Mendis, N.; Ayuso-Mateos, J. L.; Saxena, S.OBJECTIVE: Schizophrenia is a highly disabling disease and is costly to treat. We set out to establish what are the most cost-effective interventions applicable to developing regions and countries. METHODS: Analysis was undertaken at the level of three WHO subregions spanning the Americas, Africa and South-East Asia, and subsequently in three member states (Chile, Nigeria and Sri Lanka). A state transition model was used to estimate the population-level health impact of older and newer antipsychotic drugs, alone or in combination with psychosocial intervention. Total population-level costs (in international dollars or local currencies) and effectiveness (measured in disability-adjusted life years averted) were combined to form cost-effectiveness ratios. FINDINGS: The most cost-effective interventions were those using older antipsychotic drugs combined with psychosocial treatment, delivered via a community-based service model (I$ 2350-7158 per disability-adjusted life year averted across the three subregions, I$ 1670-3400 following country-level contextualisation within each of these subregions). The relative cost-effectiveness of interventions making use of newer, "atypical" antipsychotic drugs is estimated to be much less favourable. CONCLUSION: By moving to a community-based service model and selecting efficient treatment options, the cost of substantially increasingtreatment coverage is not high (less than I$ 1 investment per capita). Taken together with other priority-setting criteria such as disease severity, vulnerability and human rights protection, this study suggests that a great deal more could be done for persons and families living under the spectre of this disorder