Browsing by Author "Jayaweera, P.M."

Now showing 1 - 2 of 2

Green Synthesis of TiO2 Nanoparticles: A Cost Effective Approach.
(In: Proceedings of the International Postgraduate Research Conference 2017 (IPRC – 2017), Faculty of Graduate Studies, University of Kelaniya, Sri Lanka., 2017) Fernando, S.S.N.; Peiris, M.M.K.; Gunasekara, T.D.C.P.; Arachchi, N.D.H.; Jayaweera, P.M.
Titanium dioxide (TiO2) nanoparticles (NPs) are very useful for many purposes due to their unique physical and chemical properties. Biological synthesis of TiO2 NPs is poorly understood compared to chemical and physical synthesis methods. The present investigation was undertaken to synthesize TiO2 NPs using Baker‘s Yeast by a low-cost and sustainable process. For yeast mediated TiO2 NP synthesis, yeast was cultured in sterile filtered 5% (w/v) glucose solution and incubated for 24 h. After that, TiCl3 was added slowly until a clear purple solution observed. Then the solution was allowed to stand at room temperature under dark conditions for three days. The solution was centrifuged and the precipitate was washed several times with sterile distilled water, dried at room temperature and oven-dried at heating periods of 250, 350, 450, 550, 650 and 750 oC for 2 h. Characterization of synthesized TiO2 NPs was performed using X-ray diffraction (XRD), Transmission Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM). Spherical TiO2 NPs were observed with a large amount of thin TiO2 lamellas. Lamellas were consisted of a large number of small TiO2 NPs. XRD pattern of the NPs obtained by using yeast template was assigned to be pure anatase TiO2 according to characteristic peak positions at 25.303 (1,0,1), 37.78 (1,0,3), 48.03 (2,0,0), 54.45 (1,0,5), 62.80 (2,1,3), 70.34 (2,2,0), 74.91(1,0,7) and 82.81 (3,0,3) degrees. The most predominant orientation was the (1,0,1) plane as the highest intensity was observed at 25.303. The particle size distribution was 3.6 – 12.0 nm with a mean particle size of 6.7 ± 2.2 nm as shown in TEM imaging. In this study, TiO2 NPs were synthesized with TiCl3 as the precursor salt, in an eco-friendly manner. The increased temperature induced crystallinity. Anatase phase TiO2 NPs get converted into rutile phase within 600-700 oC range. The biosynthesized anatase TiO2 NPs were thermally stable. Yeast cells were used as a biotemplate that can facilitate Ti3+ adsorption followed by nucleation. The NPs were smaller with a narrow size distribution. The results suggest that Yeast mediated TiO2 NP synthesis is a renewable and eco-friendly alternative to chemical synthesis.
Homogeneity-driven technology independence in HL7 paradigms
(Department of Zoology and Environmental Management, University of Kelaniya, Kelaniya, Sri Lanka., 2016) Sabar, M.I.; Jayaweera, P.M.; Edirisuriya, E.A.T.A.
Semantic Interoperability (SI) is key in all Information Technology based healthcare information exchange amongst participating enterprises. It is the regulated, meaningful exchange and access to valued healthcare information. Coined International Interoperability herein, SI is the principle goal of this study. The predominant exponent of SI is Health Level Seven (HL7) v3, a global healthcare standard in operation today. It was determined that infusing simplicity and uniformity in the labyrinths of the HL7 sub-processes would derive optimal analytic and design interoperability. Even allied activities such as domain requirements cross-checking, stakeholder consensus, and audit, will be significantly enhanced by this process. The HL7 v3 development process consisting of Messages, Clinical Document Architecture (CDA), and Services, is presently modelled using the Extended Markup Language (XML) which actually introduces wordiness, non-uniformity, and ambiguity into the HL7 specifications development paradigm. Introduced in 1996, it is best used for formatting documents, making them human and machine readable, and also web-ready. Its primary purpose and focus is data presentation and reporting, less modelling complex ontological and information architectures. Our proposed solution remodels all such artifacts using the newly devised Unified Data Atom (UDA+) vocabulary creating overarching homogeneity across all three HL7 paradigmic landscapes. It has also been proved in this study that the transformation from XML to HL7 vocabulary is equivalent and complete, meaning that the transformation is syntactically equivalent, semantically precise, and complete. Working towards directly inducing inter-paradigmic (ie., Messages, Documents, and Services), Reference Information Model (RIM), or HL7 Ontology related efficiencies and enhancements generates meagre returns, since these top-level interfaces have been researched and any benefits already accrued and utilized. Further, the use of multiple ontological and informational-structure related modelling technologies such as Web Ontology Language (OWL), and XML actually subvert interoperability and communication processes in the HL7 specifications development paradigm. This paper however focused on excavating and capitalizing on the abounding interoperability potential afforded by core paradigm-related specification development sub-processes. UDA+-modelled artifacts accrue inclusive benefits of simplicity, brevity, and versatility over the previous XML representation. True sub-process interoperability during design and development is achieved, promoting high-calibre, internationally-interoperable and inclusively-efficient system development. Principally significant is that analysis and design interoperability amongst all stakeholders also derived, actualizing overarching, ubiquitous exchange.