Browsing by Author "Anwar, N."
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Item Significance, Symbolism and Representation of Elephants in Gandhara Buddhist Art(Centre for Asian Studies, University of Kelaniya, Sri Lanka, 2016) Anwar, N.Elephant being the symbol of stature, prosperity, wisdom and dominance is the most represented animal in the antiquity of South Asia. Since the dawn of Bronze Age, the depictions of elephants remained the choice of artists on priority basis. Similarly, the sculpting of elephants also remained a focal point during the Buddhist occupation of the historic Gandhara, the ancient name of present day north-western parts of Pakistan, the holy land of Buddhism. Around the end of the first century BC, it gave birth to a Sculpting Art devoted to the faith of the Buddha. The art was not a natural continuation of the Ancient Indian Arts but exhibits clear evidence of Hellenistic influence, though, it is significant to elaborate that the purpose of this art was the propagation of Buddhism through the images carved revolving around the Buddha’s life stories and other associated legends. So far, the case of elephant depictions is concerned, preliminary, the birth of the Buddha drawn by an elephant to miracles and up to representation in architecture, elephant continued to be the most celebrated animal in the Gandharan panels. The present research is an attempt on one side towards the significance and symbolism of elephant depicted in various postures where, on other side to eliminate on zonal workshops based on stylistic ground. Since the basic problem with the Gandharan sculptures is the absence of provenances, especially, those recovered in the early nineteenth century, the stylistic study is always adopted for affixing them to their probable zones. Similarly, the paper will also make an effort to reconstruct the glorious faunal past of that zone.Item Uses of a familial adenomatous polyposis registry(Sri Lanka Medical Association, 2011) Dalpatadu, K.U.A.; Anwar, N.; Wijesuriya, S.R.E.; Kumarage, S.K.; Amarasinghe, B.; Deen, K.I.OBJECTIVES :To improve the prognosis of patients with familial adenomatous polyposis (FAP) by early diagnosis and prophylactic treatment through a coordinated FAP register. DESIGN: The establishment and descriptive analysis of the prospective database of the FAP registry. SETTING: University surgical unit, Colombo North Teaching Hospital Ragama, Sri Lanka. PATIENTS : Probands were identified by tracing all diagnosed FAP patients from 1996 to 2010 and their family members at risk. INTERVENTIONS :The establishment of a polyposis register included the following stages: ascertainment of probands (first contact symptomatic FAP patients), construction of pedigrees, counselling relatives and prophylactic screening of family members at risk, treatment and follow up. RESULTS : Twenty seven enrolled probands (12 male and 15 female, age 11-52 years, median age 34 years) were investigated. Pedigree analyses showed 206 relatives at risk. Twenty four family members at risk were screened of a total of 51 registered individuals. The rate of spontaneous mutations was 41%. Thirty five were diagnosed with FAP. Eight were screen detected (median age – 32 years) and 27 symptomatic (median age – 34 years). Concomitant colorectal cancer was detected in 17 (63%) symptomatic individuals and in 1 (13%) screen detected individual. Colectomy was performed in 27 (77%) patients while 8 (23%) are on chemoprophylaxis. Congenital hypertrophic retinal pigment epithelium was detected in 15. Desmoids tumours (6%) and other extraintestinal manifestations including osteomas, sebacious cysts and dental abnormalities (34%) were also detected. A thyroid gland malignancy was screen detected while retinoblastoma, hepatoblastoma and cerebral tumours were seen in pedigrees. CONCLUSIONS :A polyposis register may improve prognosis of FAP by early detection. It will help coordinate, optimise and streamline clinical management of patients with FAP and their relatives at risk.