Browsing by Author "Abeyratne, P.D."

Now showing 1 - 2 of 2

Aetiology and other features of a cohort of adult Sri Lankans presenting with upper gastrointestinal bleeding (UGIB)
(Ceylon College of Physicians, 2010) Satarasinghe, R.L.; de Silva, A.P.; Arulnithy, K.; Abeyratne, P.D.; Jayawardana, M.A.R.
OBJECTIVES: To ascertain major causes of UGIB and other related clinical features of adult Sri Lankan using open access endoscopy facilities. DESIGN AND SETTING: 1500 upper gastrointestinal endoscopies performed by Ward-06, Sri Jayewardenepura General Hospital, Kotte from 01/03/2002 to 01/03/2004 for whatever reason was retrospectively reviewed. Those who had endoscopy for UGIB were selected for the study, and their endoscopy findings and other clinical features analysed. RESULTS: There were 342 (24%) upper GI bleeders. The mean age of presentation was 55.5 years +/-14.4 SD. A high proportion was seen between 50-70 years of age. Sex distribution was, male:female = 229:114 (2:1). 45% have presented with haematemesis, 31% with malaena, and 24% with both. Endoscopy showed the presence of severe antral gastritis and duodenitis, oesophageal varices, oesaphagitis, erosive gastropathy, portal hypertensive gastropathy, pangastritis and peptic ulcer disease in 38%, 35%, 28%, 28%, 20%, 17% and 15% of the instances respectively. Hiatus herniae were seen in 43% although its role was unclear. Often combined pathologies were seen. Only 52% of the varices showed endoscopic evidence of bleeding. Excess alcohol consumption was seen in 36% while 5% were on NSAIDs. 5% had endoscopic negatives. CONCLUSIONS: UGIB is a major problem to the endoscopist, constituting about 25% of the work load, in this part of the continent. Although approximately 50% of the varices found had bled, portal hypertension related pathologies are a cause for concern. Alcohol was a contributory factor in 1/3 of the endoscoped population. Bleeding from PUD was not a dominant feature compared to the west.
A descriptive study of gastro-intestinal (GI) malignancies of adult Sri Lankans: data from a 2 year survey in a medical unit of a tertiary referral centre
(Sri Lanka Medical Association, 2005) Satarasinghe, R.L.; de Silva, A.P.; Abeyratne, P.D.
OBJECTIVES: To describe demographics and clinico-endoscpoic features of GI malignancies of adult Sri Lankans, seeking medical advice. DESIGN AND SETTING: Data of 1491 consecutive upper GI and 327 consecutive lower GI endoscopies performed by Ward 6, SJGH Kotte, from 01/03/2002 to 01/03/2004 were retrospectively analysed. Those who had endoscopic and histological proof of GI malignancies were included in the study. RESULTS: There were 51 total GI malignancies, showing oesophageal, gastric, colo-rectal and duodenal involvement in 13, 18, 19 an 1 respectively, which was 2.8 % of the whole study population.2.1% and 5.8% revealed upper GI and lower GI malignancies in respective populations. Mean age of presentation in oesophageal, stomach, and colo-rectal carcinomas were 63.8, 70.1 and 58.3 respectively. All malignancies showed a male preponderance of 2.4:1 while in carcinoma of stomach this was 8:1 .The mean haemoglobin at presentation was 10.7, 9.0 and 9.7 g/dl for oesophageal, gastric and colo-rectal malignancies respectively. There were no other significant haernatological or bio¬chemical abnormalities at presentation. CONCLUSIONS: The study population showed three times preponderance of colo-rectal malignancies compared to those of upper GIT in respective groups. Mean age of presentation was early in carcinoma of the colon compared to other three GI malignancies (p<0.05). Anaemia was the single most significant abnormal laboratory parameter in this study.