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Browsing Conference Papers by Author "Dassanayake, A.S."

Browsing Conference Papers by Author "Dassanayake, A.S."

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  • Acute hearing loss in febrile patients: a predictor of scrub typhus 
    Premaratna, R.; Chandrasena, T.G.A.N.; Dassanayake, A.S.; Loftis, A.; Dasch, G.A.; de Silva, H.J. (Sri Lanka Medical Association, 2005)
    INTRODUCTION: Rickettsial infections are re-emerging in Sri Lanka. Complications such as pneumonitis, myocarditis and encephalitis can occur late in the disease, and result in a high mortality. Early diagnosis reduces ...
  • Aetiology of cirrhosis in a tertiary referral centre in Sri Lanka 
    Dassanayake, A.S.; Munasinghe, C.S.; Mettananda, K.C.D.; de Silva, A.P.; de Silva, H.J. (Sri Lanka Medical Association, 2007)
    INTRODUCTION: Alcoholic liver disease is believed to be the commonest cause of cirrhosis in Sri Lanka. However, with the rising prevalence of obesity and diabetes, non-alcoholic steatohepatitis (NASH) is increasingly being ...
  • Aetiology of cirrhosis in a tertiary referral centre in Sri Lanka 
    Dassanayake, A.S.; Mettananda, K.C.D.; de Silva, A.P.; de Silva, H.J. (Wiley Blackwell Scientific Publications, 2005)
    INTRODUCTION: Alcoholic liver disease is widely believed to be the commonest cause of cirrhosis in Sri Lanka. However, with the rising prevalence of obesity and diabetes, non-alcoholic steatohepatitis (NASH) is increasingly ...
  • Alanine Transaminase (ALT) levels in normal adult Sri Lankans 
    Niriella, M.A.; Dassanayake, A.S.; Kalubowila, K.; Kalubowila, U.; de Silva, A.P.; Wickremasinghe, A.R.; Kato, N.; Makaya, M.; de Silva, H.J. (American Gastroenterological Association(AGA) Institute, Published by Elsevier Inc., 2009)
    BACKGROUND : Alanine transaminase (ALT) levels are widely used in screening for liver disease.The upper limit of normal (ULN) of ALT (males 30 IU/l, females 19 IU/l) have been definedfor western populations. Normal levels ...
  • Anthropometric correlates of total body fat, visceral adiposity and cardio-metabolic health risk: a community cohort study of urban, adult Sri Lankans 
    Niriella, M.A.; de Silva, S.T.; Kasturiratne, A.; Kottachchi, D.; Ranawaka, U.K.; Dassanayake, A.S.; de Silva, A.P.; Pathmeswaran, A.; de Silva, H.J. (Sri Lanka Medical Association, 2016)
    INTRODUCTION: Anthropometric measurements (AM) are used as proxies for more direct measurements of body fat (BF) and its distribution. Several studies have examined the association between AM, BF and health outcomes such ...
  • Are alanine transaminase (ALT) levels useful to screen for Non-alcoholic Fatty Liver Disease (NAFLD) in the community? 
    Niriella, M.A.; Dassanayake, A.S.; Kalubowila, K.V.U.; Rajindrajith, S.; de Silva, A.P.; Wickremasinghe, A.R.; Kato, N.; Makaya, M.; de Silva, H.J. (Sri Lanka Medical Association, 2009)
    BACKGROUND: The value of ALT in screening for NAFLD is controversial. Furthermore, the upper limit of normal (ULN) ALT is defined for western populations but not Asian populations. Objectives: To establish ULN ALT for an ...
  • Changing phenotype of IBD in Sri Lanka 
    Niriella, M.A.; Kodisinghe, S.K.; Dinamithra, N.P.; Rajapakshe, N.; Nanayakkara, S.D.; Luke, H.P.D.P.; Silva, K.T.M.; Dassanayake, A.S.; de Silva, A.P.; Navarathne, N.M.M.; de Silva, H.J. (Sri Lanka Medical Association, 2016)
    INTRODUCTION: Inflammatory bowel disease (IBD) is increasing in Asia Pacific, with recent changes in phenotype reported from some countries. METHOD: Patients with histologically proven IBD [ulcerative colitis(UC), Crohn’s ...
  • Clinical predictors of poor outcomes in hepatocellular carcinoma of nonviral aetiology 
    Siriwardana, H.D.R.C.; Niriella, M.A.; Dassanayake, A.S.; de Silva, A.P.; Gunetilleke, B.; Pathmeswaran, A.; de Silva, H.J. (Sri Lanka Medical Association, 2017)
    INTRODUCTION & OBJECTIVES: Clinical predictors for prognosis of NASH and alcohol related (non-viral) hepatocellular carcinoma (nvHCC) is poorly described. METHODS: Patients with nvHCC, from a tertiary referral hepatobiliary ...
  • Comparison of cryptogenic and hepatitis B related hepatocellular carcinoma 
    Siriwardana, R.C.; Niriella, M.A.; Dassanayake, A.S.; de Silva, A.P.; Gunetilleke, B.; Chok, K.S.H.; Lo, C.M.; Chan, S.C.; Fan, S.T.; de Silva, S.T. (Sri Lanka Medical Association, 2016)
    INTRODUCTION AND OBJECTIVES: Viral hepatitis is the leading cause for hepatocellular carcinoma (HCC) globally. Cryptogenic or non-alcoholic fatty liver related HCC is increasing and is predominant in Sri Lanka (SL). Few ...
  • Comparison of one and two weeks of triple therapy for eradication of H. pylori: a randomized, controlled study in a tropical country 
    de Silva, H.A.; Hewavisenthi, J.; Pathmeswaran, A.; Navarathne, N.M.M; Peiris, R.; Dassanayake, A.S.; de Silva, H.J. (Wiley Blackwell Scientific Publications, 2004)
    INTRODUCTION: Resistance of H. pylori to antibiotics may be particularly high in parts of the tropics. Infection may prove difficult to eradicate in such situations, and there is some evidence of benefit in increasing ...
  • Comparison of outcomes of patients with alcoholic cirrhosis and non-alcoholic steatohepatitis (NASH) related cirrhosis 
    Senanayake, S.M.; Hewawasam, S.P.; Kumarasena, R.S.; Kasturiratne, A.; de Alwis, J.P.N.; Nandasiri, A.S.D.; Dassanayake, A.S.; de Silva, A.P.; de Silva, H.J. (Sri Lanka Medical Association, 2010)
    OBJECTIVES: Most cases of cirrhosis in Sri Lanka are alcohol induced or cryptogenic. There is mounting evidence that a high proportion of cryptogenic cirrhosis is NASFI related. Although longterm outcome of NASH-cirrhosis ...
  • Development and validation of Sinhala version of the chronic liver disease questionnaire (CLDQ) 
    Miththinda, J.K.N.D.; Ranawaka, C.; Pathmeswaran, A.; Dassanayake, A.S.; de Alwis, W.R.S.; Mufeena, M.N.F.; Senanayake, S.M.; Niriella, M.A.; de Silva, A.P.; de Silva, H.J. (Wiley Blackwell Scientific Publications, 2013)
    OBJECTIVE: The Chronic Liver Disease Questionnaire (CLDQ) is a validated tool measuring the Health Related Quality of Life among cirrhotics. Aim of this study was to develop and validate a Sinhala version of the CLDQ (sCLDQ) ...
  • Development and validation of sinhala version of the chronic liver disease questionnaire (CLDQ) for assessment of quality of life among cirrhotics 
    Ranawaka, C.K.; Pathmeswaran, A.; Senanayake, S.M.; de Alwis, R.; Mufeena, M.N.F.; Niriella, M.A.; Dassanayake, A.S.; de Silva, A.P.; de Silva, H.J. (Wiley Blackwell Scientific Publications, 2012)
    BACKGROUND AND AIM: Chronic liver disease (CLD) has a negative impact on patient quality of life (QOL). The Chronic Liver Disease Questionnaire (CLDQ) is a validated tool which measures the Health Related Quality of Life ...
  • Development and validation of sinhala version of the Chronic Liver Disease Questionnaire (CLDQ) for assessment of quality of life among cirrhotics 
    Ranawaka, C.K.; Pathmeswaran, A.; de Alwis, W.R.S.; Mufeena, M.N.F.; Wijewantha, H.S.; Senanayake, S.M.; Niriella, M.A.; Dassanayake, A.S.; de Silva, A.P.; de Silva, H.J. (Sri Lanka Medical Association, 2012)
    INTRODUCTION: Chronic liver disease (CLD) has a negative impact on patient quality of life (QOL). The Chronic Liver Disease Questionnaire (CLDQ) is a validated tool which measures the Health Related Quality of Life (HRQL) ...
  • Diffuse and nodular type hepatocellular carcinoma - a comparative study 
    Wickramarathne, S.D.J.; Jayarathne, V.S.; Siriwardana, R.C.; Liyanage, C.A.H.; Niriella, M.A.; Dassanayake, A.S.; Gunetilleke, M.B.; de Silva, A.P.; de Silva, H.J. (Sri lanka Medical Association, 2015)
    INTRODUCTION AND OBJECTIVES: Incidence of hepatocellular carcinoma (HCC) is increasing. Diffuse HCC (dHCC) is rare and data on such tumours are limited. METHOD: Ail consenting patients with HCC referred to Colombo North ...
  • Diffuse and nodular type hepatoma: a prospective, comparative study 
    Wickramarathne, S.D.J.; Jayarathne, V.S.; Siriwardana, R.C.; Niriella, M.A.; Liyanage, C.A.H.; Dassanayake, A.S.; Gunetilleke, M.B.; de Silva, H.J. (Sri Lanka Medical Association, 2014)
    INTRODUCTIONS: Incidence of hepatocellular carcinoma (HCC) is increasing. Diffuse type HCC is rare and data on such tumors are limited. METHODS: All patients referred to North Colombo Liver Unit with HCC from September ...
  • Early clinical course of IBD in Sri Lanka 
    Niriella, M.A.; Kodisinghe, S.K.; Dinamithra, N.P.; Rajapakshe, N.; Nanayakkara, S.D.; Luke, H.P.D.P.; Silva, K.T.M.; Dassanayake, A.S.; de Silva, A.P.; Navarathne, N.M.M.; de Silva, H.J. (Sri Lanka Medical Association, 2016)
    INTRODUCTION: There is very limited data on the early clinical course of IBD from Sri Lanka. METHOD: Patients with histologically proven IBD [ulcerative colitis(UC), Crohn disease(CD)] of less than 3 years duration, were ...
  • Epidemiology of non- alcoholic fatty liver disease (NAFLD) in an urban Sri Lankan population 
    Dassanayake, A.S.; Rajindrajith, S.; Kasturiratne, A.; Kalubowila, U.; de Silva, A.P.; Mizoue, T.; Makaya, M.; de Silva, H.J. (Sri Lanka Medical Association, 2008)
    BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is increasing in the Asia-Pacific region. NAFLD can progress from simple steatosis, through steatohepatitis to advanced hepatic fibrosis, cirrhosis and hepatoma. Its ...
  • Epidemiology of Non-Alcoholic Fatty Liver Disease (NAFLD) among adults in an urban Sri Lankan community 
    Dassanayake, A.S.; Rajindrajith, S.; Kasturiratne, A.; Kalubowila, U.; de Silva, A.P.; Mizoue, T.; Makaya, M.; de Silva, H.J. (American Gastroenterological Association(AGA) Institute, Published by Elsevier Inc., 2008)
    BACKGROUND - Non-alcoholic fatty liver disease (NAFLD) is increasing in the Asia-Pacific region.NAFLD can progress from simple steatosis, through steatohepatitis to advanced hepatic fibrosis, cirrhosis and hepatoma. Its ...
  • Factors affecting the clinical outcome of transarteriai chemo treatment for hepatocellular carcinoma in Sri Lankan patients 
    Jayatunge, D.S.P.; Siriwardana, H.D.R.C.; Niriella, M.A.; Dassanayake, A.S.; Liyanage, C.A.H.; Gunetilleke, M.B.; Upasena, A.; Sirigampola, C.; de Silva, A.P.; de Silva, H.J. (Sri lanka Medical Association, 2015)
    INTRODUCTION AND OBJECTIVES: Transarterial-chemo-embolization (TACE) is used for palliation of unresectable hepatocellular carcinoma (HCC). We studied the tolerability of TACE in a cohort of patients with NASH and alcoholic ...

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