Chikitsa
http://repository.kln.ac.lk/handle/123456789/4615
2024-03-29T08:09:58ZA Clinical Study on the Effect and Efficacy of Traditional Formulation Derived by Ola Leaves Manuscript in the Management of Iron Deficiency Anemia
http://repository.kln.ac.lk/handle/123456789/21200
A Clinical Study on the Effect and Efficacy of Traditional Formulation Derived by Ola Leaves Manuscript in the Management of Iron Deficiency Anemia
Wijewardana, R.A.R.R.; Dissanayake, K.G.C.
Anemia is a condition, characterized by reduction m the red blood cell volume or decrease in the concentration of hemoglobin in the blood. Iron deficiency anemia is a global public health problem among school age children which retards psychomotor development and impairs cognitive performance. Prevalence of anemia among children m Sn Lanka was 2560% as of 2016. Its highest value over the past 26 years. The treatment modalities for IDA have been unsuccessful even in this modern technologically-advanced era due to the adverse effects. Herbal chugs have been used m the treatment of IDA since ancient times. In this research, it was intended to investigate the effect of Virechana formulae in Ola leave manuscript for Iron deficiency anemia control in Sri Lankan context. For this purpose 90 patients were selected and randomly divided Into 3 groups as A, B and C. Group A was given FeS04, Group B given decoction and Group C was given decoction with Virechana. BMI, Hb count, MCV and MCH were measured. According to overall assessment the patients who treated with herbal formula With Virechana treatment (Group C) show best results and patients who treated with herbal formula m Ola leave manuscript (Group B) show better results than the Group A who treated with FeS04 in the levels of Hb count, MCV and MCH But difference of BMI of all three groups were not statistically significant. The present study evidence that the short term administration of new herbal formulation has shown significant effect in decreasing the IDA. So the new herbal formulation is an effective remedy for the management of Iron deficiency anemia among school children.
2020-01-01T00:00:00ZA Clinical Study on the Effect and Efficacy of Traditional Formulation Derived by Ola Leaves Manuscript in the Management of Overweight and Obesity
http://repository.kln.ac.lk/handle/123456789/21199
A Clinical Study on the Effect and Efficacy of Traditional Formulation Derived by Ola Leaves Manuscript in the Management of Overweight and Obesity
Jayasena, R. M. D.; Dissanayake, K.G.C.
Overweight and obesity are defined as abnormal or excessive fit accumulation that presents a risk to health. Once considered a high-income country problem, overweight and obesity are now on the rise in low and middle-income countries, particularly in urban settings. The treatment modalities have been unsuccessful even in this modern technologically-advanced era. Herbal chugs have been used in the treatment of Staulya since ancient times. Thus in this research, it was intended to investigate the effect of Vtrechana formulae in Ola leave manuscript for overweight and obesity control in Sri Lankan context. Group A was treated with herbal formula for 4 weeks duration and Group B was firstly treated with Erechana procedure and then prescribed herbal formula for two weeks duration. When analysing the results of Group B, BIMI shows a P value of 0.000 which were highly significance. The mentioned traditional herbal formula is effective for the management of overweight and obesity related parameters. But it was more effective with the combination of Virechana procedure than individual. The overall results of present study evidence that the short term administration of new herbal formulation has shown significant effect in decreasing the overweight and Obesity. So the new herbal formulation is an effective remedy for the management of Overweight and Obesity
2020-01-01T00:00:00ZAntimicrobial Efficacy of Selected Ayurveda Formula against Laboratory Specimen of Staphylococcus aureus
http://repository.kln.ac.lk/handle/123456789/21198
Antimicrobial Efficacy of Selected Ayurveda Formula against Laboratory Specimen of Staphylococcus aureus
Dissanayake, K.G.C.; Karunarathna, S. B. M. M. M.
Selected formula consisted of tllree ingredients including dried leaves of Azadirachta indica, dried seeds of Sesamum indicum and Bees' honey which is clinically use for open wounds. The current study was designed as a microbiological assay and the key objective was to evaluate the antibacterial efficacy of TNK against laboratory specimen of Staphylococcus aureus (ATCC25923). The Anti-Bacterial Sensitivity Test was conducted according to the Kirby Bauer method using Agar Well Diffusion method by comparing the effect of Amoxicillin as the positive controller and distilled water as the negative controller in triplicates. The testing drug was assessed as DI and D2 in concentration ratios respectively. Results of the study were obtained through the diameter measurement of inhibitory zone and assessed using one - sample T — test DI depicted p value as 0.024 and T - test was 4.44. D2 depicted p value as 0.100 and T- test was 1.89. Comparing to the positive control drug, the hypothesis was generated as Ho: μ ≤19 mm and H1 : μ>19 mm Referring to hypothesis, Hoof DI was rejected and HoofD2 was not rejected. The significant level was considered less tllan 5%. D2 concentration of TNK was significant against laboratory specimen of Staphylococcus aureus_ The study suggests that the TNK is consisted with an extrinsic effective antibacterial application for infected wounds which were caused by Staphylococcus aureus_ Further clinical study on human subjects will verify the efficacy of TNK in clinical manifestations.
2020-01-01T00:00:00ZManagement of Cataract with Ayurveda Treatment Modality; a Comparative Clinical Study
http://repository.kln.ac.lk/handle/123456789/21197
Management of Cataract with Ayurveda Treatment Modality; a Comparative Clinical Study
Dissanayake, K.G.C.; Srilal, U. L. N.
The comparative clinical study was designed to evaluate the effect of Anjanavarti in the management of Cataract in comparison with Virecanakarma. Thirty patients were selected, suffering from Cataract and randomly divided in to two groups as group A and B. For the group A Anyanavarti was applied after the Virecana karma for a period of thirty days. For the group B Anjanavarti was applied for a period of thirty days. After the Anjanavarti treatment in group A, visual acuity was tested by using Wilcoxon Signed Ranks test. It was significant (0.001) in 0.05 levels which can be concluded that there was considerable effect after the treatment of Anjanavarti followed by Virecanakarma. Group B also significant (0.001) in 0.05 level. Therefore, it was concluded that there was a therapeutic effect of Anjanavarti in individual application. While group A and B were compared using Mann-Whitney U test, which elaborated two groups were not identical to each other with respect to visual acuity at after the treatment. According to the mean rank and sum of ranks between two groups after treatments, it can be clearly identified that mean rank of group A is less than group B, which means that the treatment effect of Visual Acuity in group A is better than group B while considering the results after the Virecana karma p value of total cholesterol (O. 132), LDL cholesterol (0.145), TGL cholesterol (O. 147) and HDL cholesterol (Based on positive ranks ) (0.176) were not significant in 0.05 level.
2020-01-01T00:00:00Z