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Browsing by Author "Moorghen, M."

Browsing by Author "Moorghen, M."

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  • Role of SMAD proteins in colitis-associated cancer: from known to the unknown 
    Chandrasinghe, P.; Cereser, B.; Moorghen, M.; Al Bakir, I.; Tabassum, N.; Hart, A.; Stebbing, J.; Warusavitarne, J. (MacMillan Press, 2018)
    Small mothers against decapentaplegic (SMAD) proteins are a family of signal transduction molecules in transforming growth factor β (TGFβ) ligand pathways that have been found to have a key role in the pathogenesis of ...
  • SMAD7 shows a biphasic expression pattern during progression of ulcerative colitis-associated colorectal cancer 
    Chandrasinghe, P.; Cereser, B.; Moorghen, M.; Spaggiari, P.; Maroli, A.; Del Bel Belluz, L.; Hart, A.; Spinelli, A.; Stebbing, J.; Warusavitarne, J. (Oxford University Press, 2019)
    BACKGROUND: Ulcerative colitis (UC) is an idiopathic inflammation of the intestine with an increased risk of developing colitis-associated cancer (CAC). Currently, clinical trials are underway aiming to inhibit SMAD7 to ...

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