Blacksell, S.D.Tanganuchitcharnchai, A.Jarman, R.G.Gibbons, R.V.Paris, D.H.Bailey, M.S.Day, N.P.Premaratna, R.Lalloo, D.G.de Silva, H.J.2014-10-292014-10-292011Clinical and Vaccine Immunology; 18(10): pp.1773-751556-6811 (Print)1556-679X (Electronic)http://repository.kln.ac.lk/handle/123456789/2035A Sri Lankan fever cohort (n = 292 patients; 17.8% prevalence) was used to assess two standard diagnostic Chikungunya IgM tests. The immunochromatographic test (ICT) acute sample sensitivity (SN) was 1.9 to 3.9%, and specificity (SP) was 92.5 to 95.0%. The enzyme-linked immunosorbent assay (ELISA) gave an acute sample SN of 3.9% and an SP of 92.5% and a convalescent sample SN of 84% and an SP of 91%. These assays are not suitable for the acute diagnosis of Chikungunya virus infection.Article