Fernando, M.Tillakaratne, S.Gunetilleke, B.Liyanage, C.Appuhamy, C.Weerasuriya, A.Dissanayake, J.Siriwardana, R.2024-01-242024-01-242023Ceylon Medical Journal.2023;68(1):25–28.0009-0875 (Print)2386-1274 (Electronic)http://repository.kln.ac.lk/handle/123456789/27439Not Indexed in MEDLINELiver transplant (LT) is the standard therapy for medically refractory acute liver failure (ALF). Finding a deceaseddonor graft in an emergency is challenging and often overcome by living-donation. Blood group matching is practised for LT though ABO-incompatible liver transplant (ABOi-LT) is performed inselected circumstances. We report an infant who underwent successful ABOincompatible living donor LT for ALF of unknown aetiology. This being the country’s first ABOi-LT, the youngest LT recipient to date and the youngest receiving emergency LT for ALF; we describe the novel experience at a resource-limited setting in Sri Lanka (SL).enABO-incompatible liver transplantLiving donorInfantAcute liver failureSri LankaArticle