Jeyapraniya, A.de Silva, S.2023-10-042023-10-042023Cureus.2023;15(9):e459052168-8184 (Electronic)http://repository.kln.ac.lk/handle/123456789/26715Not Indexed in MEDLINE in PUBMEDWhen a patient with cryoglobulinemic vasculitis develops a concurrent liver disease, it is typically associated with hepatitis C. Here, we report the case of a patient with cryoglobulinemic vasculitis and autoimmune hepatitis. A 54-year-old previously healthy woman presented with chronic urticaria. A skin biopsy revealed leukocytoclastic vasculitis and elevated serum cryoglobulins, leading to a diagnosis of cryoglobulinemic vasculitis. She also had abnormal liver functions, high IgG levels, positive antinuclear antibodies, and anti-smooth muscle antibodies. Liver biopsy revealed interface hepatitis confirming the diagnosis of autoimmune hepatitis. This case represents the rare occurrence of autoimmune hepatitis in a patient with cryoglobulinemic vasculitis.enUrticariaVasculitisCryoglobulinemiaHepatitisAutoimmuneArticle