Please use this identifier to cite or link to this item: http://repository.kln.ac.lk/handle/123456789/2251
Title: Posterior reversible encephalopathy syndrome in a survivor of valproate-induced acute liver failure: a case report
Authors: Mettananda, S.
Fernando, A.D.
Ginige, N.
Issue Date: 2013
Publisher: BioMed Central
Citation: Journal of Medical Case Reports; 7(1): 144
Abstract: INTRODUCTION: Posterior reversible encephalopathy syndrome is an extremely rare radiological diagnosis that has not been reported previously in association with acute liver failure. CASE PRESENTATION: A 6-year-old Sri Lankan girl developed acute liver failure with severe hepatic encephalopathy due to sodium valproate. She was successfully treated medically with N-acetylcysteine and L-carnitine. During recovery she again developed features of encephalopathy and had repeated convulsions associated with moderate hypertension. The diagnosis of posterior reversible encephalopathysyndrome was made on clinical and radiological grounds and she showed a gradual improvement with control of blood pressure. CONCLUSIONS: This report adds to the evidence behind treatment of valproate-induced acute liver failure with N-acetylcysteine and L-carnitine and illustrates a rare but interesting association between acute liver failure and posterior reversible encephalopathy syndrome
Description: Indexed in Scopus; In PUBMED; Not in MEDLINE
URI: http://repository.kln.ac.lk/handle/123456789/2251
ISSN: 1752-1947 (Electronic)
Appears in Collections:Journal/Magazine Articles

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