Evaluation of effectiveness of iron-folate supplementation and anthelmintic therapy against aneamia in pregnancy - a study in the plantation sector of Sri Lanka
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Date
1994
Journal Title
Journal ISSN
Volume Title
Publisher
American Society of Clinical Nutrition
Abstract
Intervention measures against anemia available to plantation workers during pregnancy include fortified food supplements (thriposha) and iron-folate supplements containing 60 mg elemental Fe. The effectiveness of these intervention measures was studied in 195 subjects whose iron and nutritional status were assessed at < 24 and > 32 wk of gestation. Taking thriposha conferred no significant benefit on maternal nutritional status, probably because sufficient amounts were not consumed. An increase in the duration of iron-folate supplementation to > 17 wk caused a significant positive change (P < 0.01) in hemoglobin, whereas an increase in the dose frequency had no significant benefit. Anthelminthic therapy in addition to iron-folate supplements caused a significant positive change in hemoglobin (P < 0.001) and serum ferritin (P < 0.005) compared with no supplementation. Thus, anthelminthic therapy significantly increased the beneficial effects of iron supplementation on hemoglobin concentration and iron status.
Description
Indexed in MEDLINE
Keywords
Anemia, Anemia-prevention and control, Anthelmintics-therapeutic use, Body Mass Index, Folic Acid-therapeutic use, Iron-administration and dosage, Iron-therapeutic use, Nutritional Status, Pregnancy, Pregnancy Complications, Pregnancy Complications-prevention and control, Pregnancy Complications, Parasitic-drug therapy
Citation
American Journal of Clinical Nutrition. 1994; 60(2): pp.286-292